Skip to main content

Table 5 Increased (or decreased) pharmacokinetic parameters values and percent change of fenofibrate after consumption of food, relative to fasted state

From: A mechanism-based pharmacokinetic model of fenofibrate for explaining increased drug absorption after food consumption

  Standard meal (686.3 kcal) High fat meal (908 kcal)
k g 0.067 h− 1 (+ 61.7%)
k m&a 0.23 h− 1 (+ 16.5%) 0.24 h− 1 (+ 21.8%)
Vc/F 7.82 L (− 39.4%) 6.95 L (− 46.1%)