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Table 4 CYP3 A4, CYP3 A5 and ABCB1 genetic equilibrium test of genetic polymorphisms

From: Effect of CYP3 A4, CYP3 A5 and ABCB1 gene polymorphisms on the clinical efficacy of tacrolimus in the treatment of nephrotic syndrome

SNP Number of examples (theoretical) Genotype frequency Allele frequency χ2 P
CYP3 A4
 *1/*1 56 (59.29) 0.56 *1 = 0.77 3.45 0.06
 *1/*1G 42 (35.42) 0.42    
 *1G/*1G 2 (5.29) 0.02 *1G = 0.23   
CYP3 A5
 *1/*1 8 (6.76) 0.08 *1 = 0.26 0.42 0.52
 *1/*3 36 (38.48) 0.36    
 *3/*3 56 (54.76) 0.56 *3 = 0.74   
ABCB1 C1236T
 CC 10 (10.24) 0.10 C = 0.32 0.012 0.91
 CT 44(43.52) 0.44    
 TT 46 (46.24) 0.46 T = 0.68   
ABCB1 G2677 T/A
 GG 13 (17.22) 0.13 G = 0.415 3.03 0.08
 GT/A 57 (48.56) 0.57    
 AA/TT/TA 30 (34.22) 0.30 T/A = 0.585