Skip to main content

Table 3 Distribution of drug-ADR pairs according to ATC classification (level I), overall and stratified according to seriousness, preventability and off-label use

From: Characterization of serious adverse drug reactions as cause of emergency department visit in children: a 5-years active pharmacovigilance study

 

Tot drug-ADR pairs

N (% out of 1100)

Seriousness

N (% out of ATC level I)

Preventability

N (% out of ATC level I)

Off-label use

N (% out of ATC level I)

Related to Vaccines

389 (35.36)

109 (28.02)

27 (6.94)

Not related to Vaccines (ATC level I)

711 (64.64)

226 (31.79)

172 (24.19)

62 (8.72)

 J - Antinfectives for systemic use (excluded vaccines - J07)

288 (40.51)

69 (23.96)

15 (5.21)

2 (0.69)

 N - Nervous system

168 (23.63)

81 (48.21)

82 (48.81)

18 (10.71)

 A - Alimentary tract and metabolism

59 (8.30)

16 (27.12)

25 (42.37)

3 (5.08)

 M - Musculoskeletal system

53 (7.45)

18 (33.96)

9 (16.98)

0 (0.00)

 C - Cardiovascular system

39 (5.49)

17 (43.59)

22 (56.41)

18 (46.15)

 H - Systemic hormonal preparations

31 (4.36)

7 (22.58)

6 (19.35)

5 (16.13)

 R - Respiratory system

27 (3.80)

3 (11.11)

2 (7.41)

3 (11.11)

 L - Antineoplastic and immunomodulating agents

13 (1.83)

4 (30.77)

2 (15.38)

2 (15.38)

 B- Blood and blood-forming organs

11 (1.55)

6 (54.55)

3 (27.27)

5 (45.45)

 D - Dermatologicals

10 (1.41)

3 (30.00)

1 (10.00)

0 (0.00)

 G - Genitourinary system and sex hormones

4 (0.56)

2 (50.00)

4 (100.00)

4 (100.00)

 P - Antiparasitic products

4 (0.56)

0 (0.00)

0 (0.00)

0 (0.00)

 S - Sensory organs

4 (0.56)

0 (0.00)

1 (25.00)

2 (50.00)