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Fig. 5 | BMC Pharmacology and Toxicology

Fig. 5

From: Classification and prediction of toxicity of chemicals using an automated phenotypic profiling of Caenorhabditis elegans

Fig. 5

Method design. Mainly there are three steps in our method: (1) culture worms in 384-well plates with different chemicals and take video for each well; (2) process these videos, get each frame, reduce the uneven illumination, segment the image, and then quantify phenotypes for worms under each chemical treatment; (3) characterize different chemicals and their toxicities based on these quantified phenotypes

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