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Table 1 Physical appearance and plasma biochemical profiles before (0 h) and 24 h after administration of puerarin at 1 mg/kg IV and 5 and 10 mg/kg PO

From: Absolute oral bioavailability and disposition kinetics of puerarin in female rats

Parameters Administration of Puerarin
1 mg/kg IV 5 mg/kg PO 10 mg/kg PO
0 h 24 h 0 h 24 h 0 h 24 h
Physical appearance Normal Normal Normal Normal Normal Normal
AST (U/L) 61.67 ± 9.36 55.83 ± 2.90 57.67 ± 5.10 56.00 ± 6.84 55.60 ± 7.96 57.40 ± 5.12
ALT (U/L) 27.00 ± 26.18 11.20 ± 16.22 26.33 ± 18.78 13.17 ± 17.40 25.00 ± 13.92 12.17 ± 9.76
Creatinine (mg/dL) 0.20 ± 0.00 0.20 ± 0.00 0.21 ± 0.02 0.21 ± 0.02 0.21 ± 0.10 0.21 ± 0.08
  1. Data are presented as mean ± S.D. (n = 4). *p < 0.05, 0 h vs. 24 h