Antibiotics | Total ADEs n (%) | LOS n (%) | Cardiaca n (%) | GITb n (%) | Ototoxicityc n (%) | Hematologyd n (%) | Hepatobiliarye n (%) | Renalf n (%) | Neurotoxicityg n (%) | Othersh n (%) |
---|---|---|---|---|---|---|---|---|---|---|
β - Lactams | ||||||||||
Penicillins | 62 (12.8) | Short LOS 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
Long LOS 62 (100.0) | 0 (0.0) | 34 (54.8) | 0 (0.0) | 2 (3.2) | 5 (8.1) | 2 (3.2) | 10 (16.1) | 9 (14.5) | ||
Carbapenem | 34 (6.9) | Short LOS 9 (26.5) | 0 (0.0) | 2 (22.2) | 0 (0.0) | 0 (0.0) | 7 (77.8) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
Long LOS 25 (73.5) | 0 (0.0) | 14 (56.0) | 0 (0.0) | 10 (40.0) | 1 (4.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | ||
Cephalosporins | 66 (13.6) | Short LOS 15 (22.7) | 0 (0.0) | 4 (26.7) | 0 (0.0) | 6 (40.0) | 2 (13.3) | 1 (6.7) | 1 (6.7) | 1 (6.7) |
Long LOS 51 (77.3) | 0 (0.0) | 10 (19.6) | 0 (0.0) | 18 (35.3) | 17 (33.3) | 5 (9.8) | 1 (1.9) | 0 (0.0) | ||
Total β – Lactams | 162 (33.3) | Short LOS 24 (14.8) | 0 (0.0) | 6 (25.0) | 0 (0.0) | 6 (25.0) | 9 (37.5) | 1 (4.2) | 1 (4.2) | 1 (4.2) |
Long LOS 138 (85.2) | 0 (0.0) | 58 (42.0) | 0 (0.0) | 30 (21.7) | 23 (16.7) | 7 (5.1) | 11 (7.9) | 9 (6.5) | ||
Non- β Lactams | ||||||||||
Aminoglycosides | 37 (7.6) | Short LOS 5 (13.5) | 0 (0.0) | 0 (0.0) | 1 (20.0) | 0 (0.0) | 0 (0.0) | 1 (20.0) | 1 (20.0) | 2 (40.0) |
Long LOS 32 (86.5) | 0 (0.0) | 5 (15.6) | 10 (31.3) | 2 (6.3) | 0 (0.0) | 10 (31.3) | 2 (6.3) | 3 (9.4) | ||
Macrolides | 61 (12.6) | Short LOS 5 (8.2) | 0 (0.0) | 1 (20.0) | 1 (20.0) | 1 (20.0) | 1 (20.0) | 0 (0.0) | 0 (0.0) | 1 (20.0) |
Long LOS 56 (91.8) | 8 (14.3) | 17 (30.4) | 10 (17.9) | 2 (3.4) | 8 (14.3) | 0 (0.0) | 1 (1.8) | 10 (17/9) | ||
Fluoroquinolones | 61(12.6) | Short LOS 17 (27.9) | 0 (0.0) | 0 (0.0) | 6 (35.3) | 2 (11.8) | 6 (35.3) | 1 (5.9) | 0 (0.0) | 2 (11.8) |
Long LOS 44 (72.1) | 7 (15.9) | 8 (18.2) | 3 (6.8) | 3 (6.8) | 9 (20.5) | 5 (11.4) | 8 (18.2) | 1 (2.3) | ||
Tetracyclines | 36 (7.4) | Short LOS 7 (19.4) | 0 (0.0) | 3 (42.9) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 2 (28.6) | 2 (28.6) |
Long LOS 29 (80.6) | 0 (0.0) | 16 (55.2) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 4 (13.8) | 9 (31.0) | ||
Lincosamide | 26 (5.4) | Short LOS 5 (19.2) | 0 (0.0) | 4 (80.0) | 0 (0.0) | 1 (20.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
Long LOS 21 (80.8) | 0 (0.0) | 15 (71.4) | 0 (0.0) | 3 (14.3) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 3 (14.3) | ||
Glycopeptide | 37 (7.6) | Short LOS 18 (48.6) | 0 (0.0) | 4 (22.2) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 8 (44.4) | 0 (0.0) | 6 (33.3) |
Long LOS 19 (51.4) | 0 (0.0) | 0 (0.0) | 8 (42.1) | 7 (36.8) | 0 (0.0) | 2 (10.5) | 0 (0.0) | 2 (10.5) | ||
Oxazolidones | 29 (5.9) | Short LOS 9 (31.0) | 0 (0.0) | 2 (22.2) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 4 (44.4) | 3 (33.3) |
Long LOS 20 (68.9) | 0 (0.0) | 7 (35.0) | 0 (0.0) | 1 (5.0) | 0 (0.0) | 0 (0.0) | 5 (25.0) | 7 (35.0) | ||
Imidazole derivative | 37 (7.6) | Short LOS 13 (35.1) | 0 (0.0) | 5 (38.5) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 8 (61.5) |
Long LOS 24 (64.9) | 0 (0.0) | 11 (40.8) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 13 (54.2) | 0 (0.0) | ||
Total non β – Lactams | 324 (66.7) | Short LOS 79 (24.4) | 0 (0.0) | 19 (24.1) | 8 (10.1) | 4 (5.1) | 7 (8.9) | 10 (12.7) | 7 (8.9) | 24 (30.4) |
Long LOS 245 (75.6) | 15 (6.1) | 79 (32.3) | 31 (12.7) | 18 (7.4) | 17 (6.9) | 17 (6.9) | 33 (13.5) | 35 (14.3) | ||
Total (β – Lactams + Non β – Lactams) | 486 (38.9) | Short LOS 103 (21.2) | 0 (0.0) | 25 (24.3) | 8 (7.8) | 10 (9.7) | 16 (15.5) | 11 (10.7) | 8 (7.8) | 25 (24.3) |
Long LOS 383 (78.8) | 15 (3.9) | 137 (35.8) | 31 (8.1) | 48 (12.5) | 40 (10.4) | 24 (6.3) | 44 (11.5) | 44 (11.5) |