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Table 5 Preventability assessment (N = 486)

From: Causality and preventability assessment of adverse drug events of antibiotics among inpatients having different lengths of hospital stay: a multicenter, cross-sectional study in Lahore, Pakistan

Schumock and Thornton criteria

Long LOS, N = 383,

n (%)

Short LOS, N = 103,

n (%)

Total, N = 486,

n (%)

Section A: Definitely preventable ADEs

 Was there a history of allergy or previous reaction to the drug?

4 (1.0)

5 (4.9)

9 (1.9)

 Was the drug involved inappropriate for the patient’s clinical condition?

100 (26.1)

14 (13.6)

114 (23.5)

 Was the dose, route, or frequency of administration inappropriate for patient’s age, weight or disease state?

53 (13.8)

11 (10.7)

64 (13.2)

 Was toxic serum drug concentration or lab monitoring test documented?

7 (1.8)

9 (8.7)

16 (3.3)

 Was there a known treatment for ADEs?

7 (1.8)

2 (1.9)

9 (1.9)

Total

171 (44.7)

41 (39.8)

212 (43.6)

Section B: Probably preventable ADEs

 Was therapeutic drug monitoring or other necessary lab test not performed?

31 (8.1)

7 (6.8)

38 (7.8)

 Was the drug interaction involved in ADEs?

4 (1.0)

2 (1.9)

6 (1.2)

 Was poor compliance involved in ADE?

13 (3.4)

4 (3.9)

17 (3.5)

 Were preventative measures not prescribed or administered to the patient?

8 (2.1)

3 (2.9)

11 (2.3)

Total

56 (14.6)

16 (15.5)

72 (14.8)

Total (preventable ADEs)

227 (59.3)

57 (55.3)

284 (58.4)

Section C: Non-preventable ADEs or ADRs

 If all the above criteria not fulfilled.

156 (40.7)

46 (44.7)

202 (41.6)

  1. LOS Length of stay ADEs Adverse drug events ADRs Adverse drug reactions