Table 6 Adverse drug events with respect to class of prescribed antibiotics (N = 486)
Antibiotics | ATC code | Definitely preventable ADEs | Probably preventable ADEs | Non-preventable ADEs | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
Long LOS, N = 171, n (%) | Short LOS, N = 41, n (%) | Total, N = 212, n (%) | Long LOS, N = 56, n (%) | Short LOS, N = 16, n (%) | Total, N = 72, n (%) | Long LOS, N = 156, n (%) | Short LOS, N = 46, n (%) | Total, N = 202, n (%) | ||
β - Lactams | ||||||||||
Penicillins | J01C | 25 (14.6) | 0 (0.0) | 25 (11.8) | 9 (16.1) | 0 (0.0) | 9 (12.5) | 28 (17.9) | 0 (0.0) | 28 (13.9) |
Carbapenem | J01DH | 11 (6.4) | 7 (17.1) | 18 (8.5) | 2 (3.6) | 0 (0.0) | 2 (2.8) | 12 (7.7) | 2 (4.4) | 14 (6.9) |
Cephalosporins | J01D | 26 (15.2) | 5 (12.2) | 31 (14.6) | 6 (10.7) | 0 (0.0) | 6 (8.3) | 19 (12.2) | 10 (21.7) | 29 (14.4) |
Total β – Lactams | 62 (36.2) | 12 (29.3) | 74 (34.9) | 17 (30.4) | 0 (0.0) | 17 (23.6) | 59 (37.8) | 12 (26.1) | 71 (35.2) | |
Non- β Lactams | ||||||||||
Flouroquinolones | J01 M | 18 (10.5) | 3 (7.3) | 21 (9.9) | 7 (12.5) | 6 (37.5) | 13 (18.1) | 19 (12.2) | 8 (17.4) | 27 (13.4) |
Aminoglycosides | J01G | 13 (7.6) | 3 (7.3) | 16 (7.6) | 6 (10.7) | 0 (0.0) | 6 (8.3) | 13 (8.3) | 2 (4.4) | 15 (7.4) |
Tetracyclines | J01AA | 12 (7.0) | 1 (2.4) | 13 (6.1) | 5 (8.9) | 3 (18.8) | 8 (11.1) | 12 (7.7) | 3 (6.5) | 15 (7.4) |
Macrolides | J01FA | 27 (15.8) | 4 (9.8) | 31 (14.6) | 4 (7.1) | 0 (0.0) | 4 (5.6) | 25 (16.0) | 1 (2.2) | 26 (12.9) |
Lincosamide | J01FF | 4 (2.3) | 1 (2.4) | 5 (2.4) | 10 (17.8) | 0 (0.0) | 10 (13.9) | 7 (4.5) | 4 (8.7) | 11 (5.5) |
Glycopeptide | J01XA | 9 (5.3) | 8 (19.5) | 17 (8.0) | 2 (3.6) | 2 (12.5) | 4 (5.6) | 8 (5.1) | 8 (17.4) | 16 (7.9) |
Oxazolidones | J01XX | 13 (7.6) | 3 (7.3) | 16 (7.6) | 1 (1.8) | 3 (18.8) | 4 (5.6) | 6 (3.9) | 3 (6.5) | 9 (4.5) |
Imidazole derivatives | G01AF | 13 (7.6) | 6 (14.6) | 19 (8.9) | 4 (7.1) | 2 (12.5) | 6 (8.3) | 7 (4.5) | 5 (10.9) | 12 (5.9) |
Total Non β – Lactams | 109 (63.7) | 29 (70.7) | 138(65.1) | 39 (69.6) | 16(100.0) | 55 (76.4) | 97 (62.2) | 34 (73.9) | 131(64.9) | |