Skip to main content

Table 9 Logistic regression analysis of factors associated with Adverse drug events (N = 1249)

From: Causality and preventability assessment of adverse drug events of antibiotics among inpatients having different lengths of hospital stay: a multicenter, cross-sectional study in Lahore, Pakistan

Characteristics

ADEs

OR

95% CI

p-value

Yes

n (%)

No

n (%)

Gender

 Male

293 (23.5)

423 (33.9)

1.0

 Female

193 (15.5)

340 (27.2)

0.047

0.018─0.121

< 0.001

Age

 Children (≤18 years)

184 (14.7)

200 (16.0)

1.0

 Adults (> 18 years)

302 (24.2)

563 (45.1)

0.041

0.013─0.130

< 0.001

Co-morbidities

 Diabetes

210 (16.8)

316 (25.3)

1.0

 Asthma

169 (13.5)

255 (20.4)

0.808

0.598─1.093

0.167

 Tuberculosis

37 (3.0)

100 (8.0)

0.304

0.186─0.497

< 0.001

 Cystic fibrosis

70 (5.6)

92 (7.4)

0.527

0.334─0.829

0.006

Reasons of prescribing antibiotics

 Urinary tract infections

198 (15.9)

264 (21.1)

1.0

 Acute respiratory tract infections

157 (12.6)

205 (16.4)

0.004

0.001─0.019

< 0.001

 Soft tissue infections

131 (10.5)

156 (12.5)

0.049

0.018─0.133

< 0.001

 Skin infections

0 (0.0)

138 (11.0)

0.000

0.000─0.000

0.994

Number of antibiotics prescribed per prescription

 1

101 (8.1)

128 (10.2)

1.0

 2

153 (12.2)

450 (36.0)

0.455

0.319─0.650

< 0.001

 3

232 (18.6)

185 (14.8)

1.529

1.063─2.198

0.022

LOS

 Short (< 5 days)

103 (30.7)

610 (48.8)

1.0

 Long (≥5 days)

383 (8.2)

153 (12.2)

14.825

11.198─19.627

< 0.001

  1. ADEs Adverse drug events, OR Odd Ratio, CI Confidence Interval, LOS Length of stay. The variables with p-value <0.05 are significantly associated with adverse drug events