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Table 2 Gene regulated by cationic liposomes in the HepG2 cell

From: Cationic liposomes induce cytotoxicity in HepG2 via regulation of lipid metabolism based on whole-transcriptome sequencing analysis

Gene ID

Gene Symbol

Description

Log2FC

FDR

50,487

PLA2G3

Group 3 secretory phospholipase A2

−3.02

2.88E-02

28,965

SLC27A6

cDNA, FLJ94000, highly similar to Homo sapiens solute carrier family 27 (fatty acid transporter), member 6 (SLC27A6), mRNA

−1.47

7.5E-03

112,817

HOGA1

4-hydroxy-2-oxoglutarate aldolase, mitochondrial

−1.23

3.6E-03

1612

DAPK1

Death-associated protein kinase beta

−1.20

0

64,332

NFKBIZ

NF-kappa-B inhibitor zeta

−1.04

1E-05

7108

TM7SF2

Transmembrane 7 superfamily member 2, isoform CRA_a

−0.95

9.9E-03

1717

DHCR7

7-dehydrocholesterol reductase, isoform CRA_a

−0.82

5.18E-11

4047

LSS

cDNA, FLJ92849, highly similar to Homo sapiens lanosterol synthase (2,3-oxidosqualene-lanosterolcyclase) (LSS), mRNA

−0.66

1.59E-05

55,332

DRAM1

DNA damage-regulated autophagy modulator protein 1

−0.60

4.44E-02

79,644

SRD5A3

Polyprenolreductase

0.75

2.75E-04

1109

AKR1C4

Aldo-ketoreductase family 1 member C4

1.00

6.59E-07

3162

HMOX1

Heme oxygenase 1

1.21

3.12E-03

5166

PDK4

Pyruvate dehydrogenase kinase, isoenzyme 4

2.54

0