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Table 2 Comparison of NP and PF effect on lipogenic attributes on rat adipose tissue and human preadipocyte

From: An inhibitor of 11-β hydroxysteroid dehydrogenase type 1 (PF915275) alleviates nonylphenol-induced hyperadrenalism and adiposity in rat and human cells

   mRNA Protein
   PPARα PPARγ FASN PPARα PPARγ FASN
Rat NP vs. control n.s.a p < 0.01a increase n.s.a p < 0.05 decrease n.s. n.s.a
NP + PF vs. NP n.s.a p < 0.01a decrease p < 0.05a decrease p < 0.01 increase p < 0.01 decrease n.s.a
Human NP vs. control n.s. p < 0.05 increase p < 0.05 increase p < 0.01 decrease n.s. n.s.
NP + PF vs. NP p < 0.05 increase p < 0.05 decrease p < 0.05 decrease p < 0.05 increase p < 0.05 decrease p < 0.05 decrease
  1. n.s not significant; adata from previous report (Chang et al. 2016) [17]