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Table 2 Comparison of NP and PF effect on lipogenic attributes on rat adipose tissue and human preadipocyte

From: An inhibitor of 11-β hydroxysteroid dehydrogenase type 1 (PF915275) alleviates nonylphenol-induced hyperadrenalism and adiposity in rat and human cells

  

mRNA

Protein

  

PPARα

PPARγ

FASN

PPARα

PPARγ

FASN

Rat

NP vs. control

n.s.a

p < 0.01a increase

n.s.a

p < 0.05 decrease

n.s.

n.s.a

NP + PF vs. NP

n.s.a

p < 0.01a decrease

p < 0.05a decrease

p < 0.01 increase

p < 0.01 decrease

n.s.a

Human

NP vs. control

n.s.

p < 0.05 increase

p < 0.05 increase

p < 0.01 decrease

n.s.

n.s.

NP + PF vs. NP

p < 0.05 increase

p < 0.05 decrease

p < 0.05 decrease

p < 0.05 increase

p < 0.05 decrease

p < 0.05 decrease

  1. n.s not significant; adata from previous report (Chang et al. 2016) [17]
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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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