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Table 4 Effect of L-asparaginase on tumor size in mice after treatment

From: Purification, characterization and immunogenicity assessment of glutaminase free L-asparaginase from Streptomyces brollosae NEAE-115

Treatment Tumor size (mm3)
Day 0 Day 14 ΔT/ΔC (%) % Inhibition
Control 69.0 ± 2.2 585.0 ± 40.8 100 0
Commercial L-asparaginase 67.0 ± 4.5 240.7 ± 9.4* 33 67
Streptomyces brollosae NEAE-115 L-asparaginase 77.6 ± 3.7 188.3 ± 8.33$ 21 79
  1. Data are expressed as mean ± SEM, n = 6
  2. * Significantly different from control group using One-Way ANOVA followed by Tukey-Kramer multiple comparisons test (P < 0.05). $ Significantly different from commercial L-asparaginase-treated group using One-Way ANOVA followed by Tukey-Kramer multiple comparisons test (P < 0.05). Mann-Whitney U test, *P < 0.05