Purification, characterization and immunogenicity assessment of glutaminase free L-asparaginase from Streptomyces brollosae NEAE-115

Table 4 Effect of L-asparaginase on tumor size in mice after treatment

Treatment	Tumor size (mm³)
Treatment	Day 0	Day 14	ΔT/ΔC (%)	% Inhibition
Control	69.0 ± 2.2	585.0 ± 40.8	100	0
Commercial L-asparaginase	67.0 ± 4.5	240.7 ± 9.4*	33	67
Streptomyces brollosae NEAE-115 L-asparaginase	77.6 ± 3.7	188.3 ± 8.33$	21	79

Data are expressed as mean ± SEM, n = 6
* Significantly different from control group using One-Way ANOVA followed by Tukey-Kramer multiple comparisons test (P < 0.05). $ Significantly different from commercial L-asparaginase-treated group using One-Way ANOVA followed by Tukey-Kramer multiple comparisons test (P < 0.05). Mann-Whitney U test, *P < 0.05

ISSN: 2050-6511