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Table 6 Cox regression of the CKD patients after ADR event

From: Survivability of hospitalized chronic kidney disease (CKD) patients with moderate to severe estimated glomerular filtration rate (eGFR) after experiencing adverse drug reactions (ADRs) in a public healthcare center: a retrospective 3 year study

Variables

Cencored

Events

Adj. HR

(95% CI)

p -valuec

n

(%)

n

(%)

Age category

0.934

  ≤ 49 years

34

82.9

7

25.0

1.00

(ref.)

 

 50–59 years

32

80.0

8

28.6

1.08

(0.34,3.39)

 

  ≥ 60 years

66

83.5

13

46.4

0.89

(0.31,2.58)

 

Gender

0.504

 Male

77

83.7

15

53.6

1.00

(ref.)

 

 Female

55

80.9

13

46.4

0.69

(0.23,2.08)

 

Ethnicity

0.997

 Malay

44

84.6

8

28.6

1.00

(ref.)

 

 Chinese

57

83.8

11

39.3

1.02

(0.33,3.11)

 

 Indian

29

76.3

9

32.1

1.05

(0.33,3.35)

 

BMI category

0.434

 Underweight

14

82.4

3

10.7

1.00

(ref.)

 

 Normal

58

84.1

11

39.3

0.94

(0.21,4.25)

 

 Overweight

43

79.6

11

39.3

1.47

(0.32,6.75)

 

 Obese

17

85.0

3

10.7

0.42

(0.06,2.83)

 

Smoking

0.886

 No

98

82.4

21

75.0

1.00

(ref.)

 

 Yes

34

82.9

7

25.0

0.91

(0.24,3.37)

 

Alcohol consumption

0.987

 No

113

82.5

24

85.7

1.00

(ref.)

 

 Yes

19

82.6

4

14.3

1.01

(0.20,5.03)

 

Renal replacement therapy

0.003

 Hemodialysis

52

85.2

9

32.1

1.00

(ref.)

 

 Peritoneal dialysis

10

83.3

2

7.1

0.61

(0.11,3.39)

 

 Conservative management

70

80.5

17

60.7

5.61

(1.94,16.20)

 

Renal function

0.089

 30–59 mL/min/1.73m2

46

93.9

3

10.7

1.00

(ref.)

 

 15–29 mL/min/1.73m2

22

75.9

7

25.0

2.91

(0.65,12.96)

 

  < 15 mL/min/1.73m2

64

82.5

18

64.3

5.33

(1.18,24.07)

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