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Table 6 Cox regression of the CKD patients after ADR event

From: Survivability of hospitalized chronic kidney disease (CKD) patients with moderate to severe estimated glomerular filtration rate (eGFR) after experiencing adverse drug reactions (ADRs) in a public healthcare center: a retrospective 3 year study

Variables Cencored Events Adj. HR (95% CI) p -valuec
n (%) n (%)
Age category 0.934
  ≤ 49 years 34 82.9 7 25.0 1.00 (ref.)  
 50–59 years 32 80.0 8 28.6 1.08 (0.34,3.39)  
  ≥ 60 years 66 83.5 13 46.4 0.89 (0.31,2.58)  
Gender 0.504
 Male 77 83.7 15 53.6 1.00 (ref.)  
 Female 55 80.9 13 46.4 0.69 (0.23,2.08)  
Ethnicity 0.997
 Malay 44 84.6 8 28.6 1.00 (ref.)  
 Chinese 57 83.8 11 39.3 1.02 (0.33,3.11)  
 Indian 29 76.3 9 32.1 1.05 (0.33,3.35)  
BMI category 0.434
 Underweight 14 82.4 3 10.7 1.00 (ref.)  
 Normal 58 84.1 11 39.3 0.94 (0.21,4.25)  
 Overweight 43 79.6 11 39.3 1.47 (0.32,6.75)  
 Obese 17 85.0 3 10.7 0.42 (0.06,2.83)  
Smoking 0.886
 No 98 82.4 21 75.0 1.00 (ref.)  
 Yes 34 82.9 7 25.0 0.91 (0.24,3.37)  
Alcohol consumption 0.987
 No 113 82.5 24 85.7 1.00 (ref.)  
 Yes 19 82.6 4 14.3 1.01 (0.20,5.03)  
Renal replacement therapy 0.003
 Hemodialysis 52 85.2 9 32.1 1.00 (ref.)  
 Peritoneal dialysis 10 83.3 2 7.1 0.61 (0.11,3.39)  
 Conservative management 70 80.5 17 60.7 5.61 (1.94,16.20)  
Renal function 0.089
 30–59 mL/min/1.73m2 46 93.9 3 10.7 1.00 (ref.)  
 15–29 mL/min/1.73m2 22 75.9 7 25.0 2.91 (0.65,12.96)  
  < 15 mL/min/1.73m2 64 82.5 18 64.3 5.33 (1.18,24.07)