Table 1 Source, purity and physical properties of study compounds
From: Anesthetic-sensitive ion channel modulation is associated with a molar water solubility cut-off
Compound | CAS# | MW (amu) | Pvap (mmHg) | Solubility (M) | Carbon (#) | Volume (Å3) | Source | Purity (%) |
|---|---|---|---|---|---|---|---|---|
Alcohols | ||||||||
1-octanol | 111-87-5 | 130.23 | 1.14 × 10− 1 | 9.0 × 10− 3 | 8 | 262 | Alfa Aesar | >99 |
1-nonanol | 143-08-8 | 144.25 | 4.07 × 10− 2 | 2.7 × 10− 3 | 9 | 290 | Alfa Aesar | >99 |
1-decanol | 112-30-1 | 158.28 | 1.48 × 10− 2 | 6.5 × 10− 4 | 10 | 317 | Aldrich | >99 |
1-undecanol | 112-42-5 | 172.31 | 5.10 × 10− 3 | 1.7 × 10− 4 | 11 | 344 | Acros | 98 |
1-dodecanol | 112-53-8 | 186.33 | 2.09 × 10− 3 | 4.1 × 10− 5 | 12 | 372 | TCI | 99 |
1-tridecanol | 112-70-9 | 200.36 | 8.07 × 10− 4 | 1.2 × 10− 5 | 13 | 400 | Aldrich | 97 |
1-tetradecanol | 112-72-1 | 214.39 | 1.47 × 10− 4 | 2.1 × 10− 6 | 14 | 427 | Fluka | >99 |
1-pentadecanol | 629-76-5 | 228.41 | 1.27 × 10− 4 | 4.7 × 10− 7 | 15 | 454 | Aldrich | 99 |
Aldehydes | ||||||||
nonanal | 124-19-6 | 142.24 | 5.32 × 10− 1 | 2.3 × 10−3 | 9 | 289 | Aldrich | 95 |
decanal | 112-31-2 | 156.27 | 2.07 × 10−1 | 9.8 × 10−4 | 10 | 316 | Aldrich | 98 |
undecanal | 112-44-7 | 170.29 | 8.32 × 10− 2 | 4.2 × 10− 4 | 11 | 344 | Aldrich | 97 |
dodecanal | 112-54-9 | 184.32 | 3.44 × 10−2 | 1.8 × 10−4 | 12 | 372 | TCI | 98 |
tridecanal | 10486-19-8 | 198.34 | 1.46 × 10−2 | 8.2 × 10−5 | 13 | 399 | TCI | 98 |
tetradecanal | 124-25-4 | 212.37 | 6.39 × 10−3 | 3.7 × 10− 5 | 14 | 427 | TCI | 98 |
heptadecanal | 629-90-3 | 254.45 | 6.22 × 10−4 | 3.5 × 10−6 | 17 | 509 | TCI | >97 |
octadecanal | 638-66-4 | 268.48 | 3.00 × 10−4 | 1.7 × 10− 6 | 18 | 536 | TCI | >95 |
docosanal | 57402-36-5 | 324.58 | 2.02 × 10−5 | 9.1 × 10−8 | 20 | 646 | Alfa Aesar | 98 |
Alkanes | ||||||||
butane | 106-97-8 | 58.12 | 1.92 × 103 | 1.4 × 10−3 | 4 | 156 | Matheson | 99.99 |
pentane | 109-66-0 | 72.15 | 5.27 × 102 | 4.3 × 10−4 | 5 | 184 | Aldrich | >99 |
hexane | 110-54-3 | 86.18 | 1.51 × 102 | 1.2 × 10−4 | 6 | 211 | Acros | >99 |
heptane | 142-82-5 | 100.20 | 4.52 × 101 | 3.1 × 10−5 | 7 | 239 | Acros | >99 |
octane | 111-65-9 | 114.23 | 1.42 × 101 | 6.9 × 10−6 | 8 | 267 | Acros | >99 |
nonane | 111-84-2 | 128.26 | 4.63 × 100 | 1.4 × 10− 6 | 9 | 294 | Acros | 99 |
decane | 124-18-5 | 142.28 | 1.58 × 100 | 2.6 × 10−7 | 10 | 321 | Acros | >99 |
undecane | 1120-21-4 | 156.31 | 5.64 × 10−1 | 4.2 × 10−8 | 11 | 349 | Acros | 99 |
tetradecane | 629-59-4 | 198.39 | 2.85 × 10−2 | 6.1 × 10−9 | 14 | 431 | Aldrich | >99 |
eicosane | 112-95-8 | 282.55 | 1.40 × 10−4 | 2.9 × 10−9 | 20 | 596 | Aldrich | 99 |
Alkenes | ||||||||
1-pentene | 109-67-1 | 70.13 | 6.37 × 102 | 1.4 × 10−3 | 5 | 176 | Aldrich | 99 |
1-hexene | 592-41-6 | 84.16 | 1.88 × 102 | 4.2 × 10−4 | 6 | 203 | Aldrich | >99 |
1-octene | 111-66-0 | 112.21 | 1.79 × 101 | 2.6 × 10−5 | 8 | 258 | Aldrich | 98 |
1-nonene | 124-11-8 | 126.24 | 5.77 × 100 | 7.4 × 10−6 | 9 | 286 | Aldrich | 96 |
1-decene | 872-05-9 | 140.27 | 1.92 × 100 | 1.5 × 10− 6 | 10 | 313 | Aldrich | >97 |
1-undecene | 821-95-4 | 154.29 | 6.61 × 10−1 | 2.6 × 10−7 | 11 | 341 | Aldrich | 97 |
1-dodecene | 112-41-4 | 168.32 | 2.34 × 10− 1 | 4.1 × 10−8 | 12 | 368 | Aldrich | >99 |
1-tridecene | 2437-56-1 | 182.35 | 8.56 10−2 | 5.8 × 10−9 | 13 | 396 | Aldrich | 96 |
Alkynes | ||||||||
1-hexyne | 693-02-7 | 82.14 | 1.35 × 102 | 2.9 × 10−3 | 6 | 184 | Aldrich | 97 |
1-heptyne | 628-71-7 | 96.17 | 4.35 × 101 | 6.6 × 10−4 | 7 | 212 | Acros | 99 |
1-octyne | 629-05-0 | 110.2 | 1.44 × 101 | 1.9 × 10− 4 | 8 | 239 | Acros | 99 |
1-nonyne | 3452-09-3 | 124.22 | 4.87 × 100 | 3.9 × 10− 5 | 9 | 267 | Aldrich | 99 |
1-decyne | 764-93-2 | 138.25 | 1.69 × 100 | 7.9 × 10−6 | 10 | 294 | Aldrich | 98 |
1-undecyne | 2243-98-3 | 152.28 | 6.05 × 10−1 | 1.4 × 10− 6 | 11 | 322 | TCI | 98 |
1-dodecyne | 765-03-7 | 166.30 | 2.22 × 10− 1 | 2.4 × 10−7 | 12 | 349 | TCI | 98 |
Amines | ||||||||
1-octadecanamine | 124-30-1 | 269.51 | 4.88 × 10−5 | 1.3 × 10−3 | 18 | 546 | TCI | 97 |
1-eicosanamine | 10525-37-8 | 297.56 | 8.96 × 10−6 | 2.7 × 10−4 | 20 | 601 | Rambus | 95 |
1-hexacosanamine | 14130-10-0 | 381.72 | 8.91 × 10−8 | 2.3 × 10−5 | 26 | 766 | ACC | 98 |
1-octacosanamine | 14130-12-2 | 409.77 | 2.21 × 10− 8 | 6.3 × 10−6 | 28 | 821 | ACC | 98 |
1-triacontanamine | 66214-00-4 | 437.83 | 5.85 × 10−9 | 1.8 × 10−6 | 30 | 876 | ACC | 98 |
Cycloalkanes | ||||||||
cyclopentane | 287-92-3 | 70.13 | 3.14 × 102 | 3.3 × 10−3 | 5 | 147 | Aldrich | >99 |
cyclohexane | 110-82-7 | 84.16 | 9.37 × 101 | 1.0 × 10−3 | 6 | 176 | Aldrich | >99.7 |
cycloheptane | 291-64-5 | 98.19 | 1.99 × 101 | 2.9 × 10− 4 | 7 | 206 | Aldrich | 96 |
cyclooctane | 292-64-8 | 112.21 | 4.56 × 100 | 7.2 × 10−5 | 8 | 236 | Aldrich | >99 |
cyclodecane | 293-96-9 | 140.27 | 4.47 × 10−1 | 3.2 × 10−6 | 10 | 295 | Aldrich | 95 |
cycloundecane | 294-41-7 | 154.29 | 1.85 × 10− 1 | 5.7 × 10−7 | 11 | 324 | Aldrich | 95 |
cyclododecane | 294-62-2 | 168.32 | 4.13 × 10−2 | 9.2 × 10−8 | 12 | 353 | TCI | >99 |
Ethers | ||||||||
dibutyl ether | 142-96-1 | 130.23 | 7.10 × 100 | 1.6 × 10− 2 | 8 | 277 | Aldrich | 99.3 |
dipentyl ether | 693-65-2 | 158.28 | 1.00 × 100 | 3.0 × 10−3 | 10 | 331 | Fluka | >98.5 |
dihexyl ether | 112-58-3 | 186.33 | 1.48 × 10−1 | 5.8 × 10−4 | 12 | 386 | Aldrich | 97 |
diheptyl ether | 629-64-1 | 214.39 | 2.23 × 10−2 | 1.2 × 10− 4 | 14 | 442 | TCI | 98 |
dioctyl ether | 629-82-3 | 242.44 | 4.53 × 10−3 | 2.4 × 10−5 | 16 | 497 | TCI | 98 |
didecyl ether | 2456-28-2 | 298.55 | 8.08 × 10−5 | 1.2 × 10−6 | 20 | 606 | TCI | 98 |
diundecyl ether | 43146-97-0 | 326.60 | 1.24 × 10−5 | 2.3 × 10−7 | 22 | 661 | TCI | 98 |