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Table 1 Effects of therapeutic and supra-therapeutic doses of CGV on antioxidant indices in rat testes

From: Toxicological evaluation of therapeutic and supra-therapeutic doses of Cellgevity® on reproductive function and biochemical indices in Wistar rats

Treatment

GSH

SOD

CAT

GST

MDA

Control (DW, 10 ml/kg)

21.27 ± 0.98

1.67 ± 0.14

13.00 ± 0.95

5.4 ± 0.03

1.37 ± 0.02

14.3 mg/kg

24.35 ± 1.98 (− 14.5)

3.70 ± 0.16* (− 121.6)

24.06 ± 1.98*(− 85.1)

7.78 ± 0.52*(44.1)

1.12 ± 0.03 (18.2)

28.6 mg/kg

44.05 ± 1.24**(107.1)

2.58 ± 0.34*(− 54.5)

27.00 ± 1.04*(− 107.7)

6.31 ± 0.04(− 16.9)

1.17 ± 0.01 (14.6)

1000 mg/kg

24.58 ± 1.25 (− 15.6)

1.61 ± 0.33 (3.6)

14.81 ± 0.44 (− 13.9)

4.40 ± 0.09 (18.5)

1.36 ± 0.02 (0.7)

2000 mg/kg

20.48 ± 0.55 (3.7)

1.31 ± 0.02 (21.6)

14.51 ± 0.93(− 11.6)

3.50 ± 0.01*(35.1)

1.45 ± 0.01 (− 5.8)

3000 mg/kg

19.33 ± 0.68 (10)

1.09 ± 0.15* (34.7)

10.78 ± 0.95 (17.1)

3.00 ± 0.04* (44.4)

1.35 ± 0.05 (1.5)

  1. Data are expressed as mean ± SEM. n = 6. *p < 0.05 or **p < 0.001 when compared with control group. Values in parenthesis represent % change; (−) increase; (+) decrease. Control (Distilled Water, 10 ml/kg); Superoxide dismutase; GSH Reduced glutathione (μmol/mg protein), SOD Superoxide dismutase (μmol/min/mg protein), Catalase (μmol/ml/mg protein), GST Glutathione S-transferase (μmol/ml/mg protein), MDA Malondialdehyde (nmol/mg protein)