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Table 1 Effects of therapeutic and supra-therapeutic doses of CGV on antioxidant indices in rat testes

From: Toxicological evaluation of therapeutic and supra-therapeutic doses of Cellgevity® on reproductive function and biochemical indices in Wistar rats

Treatment GSH SOD CAT GST MDA
Control (DW, 10 ml/kg) 21.27 ± 0.98 1.67 ± 0.14 13.00 ± 0.95 5.4 ± 0.03 1.37 ± 0.02
14.3 mg/kg 24.35 ± 1.98 (− 14.5) 3.70 ± 0.16* (− 121.6) 24.06 ± 1.98*(− 85.1) 7.78 ± 0.52*(44.1) 1.12 ± 0.03 (18.2)
28.6 mg/kg 44.05 ± 1.24**(107.1) 2.58 ± 0.34*(− 54.5) 27.00 ± 1.04*(− 107.7) 6.31 ± 0.04(− 16.9) 1.17 ± 0.01 (14.6)
1000 mg/kg 24.58 ± 1.25 (− 15.6) 1.61 ± 0.33 (3.6) 14.81 ± 0.44 (− 13.9) 4.40 ± 0.09 (18.5) 1.36 ± 0.02 (0.7)
2000 mg/kg 20.48 ± 0.55 (3.7) 1.31 ± 0.02 (21.6) 14.51 ± 0.93(− 11.6) 3.50 ± 0.01*(35.1) 1.45 ± 0.01 (− 5.8)
3000 mg/kg 19.33 ± 0.68 (10) 1.09 ± 0.15* (34.7) 10.78 ± 0.95 (17.1) 3.00 ± 0.04* (44.4) 1.35 ± 0.05 (1.5)
  1. Data are expressed as mean ± SEM. n = 6. *p < 0.05 or **p < 0.001 when compared with control group. Values in parenthesis represent % change; (−) increase; (+) decrease. Control (Distilled Water, 10 ml/kg); Superoxide dismutase; GSH Reduced glutathione (μmol/mg protein), SOD Superoxide dismutase (μmol/min/mg protein), Catalase (μmol/ml/mg protein), GST Glutathione S-transferase (μmol/ml/mg protein), MDA Malondialdehyde (nmol/mg protein)