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Table 2 Effects of therapeutic and supra-therapeutic doses of CGV on antioxidant indices in rat ovaries

From: Toxicological evaluation of therapeutic and supra-therapeutic doses of Cellgevity® on reproductive function and biochemical indices in Wistar rats

Treatment GSH SOD CAT GST MDA
Control 21.94 ± 1.77 17.9 ± 0.13 12.47 ± 1.46 6.3 ± 0.05 1.13 ± 0.02
14.3 59.68 ± 3.77** (− 172) 13.21 ± 1.06 (26.2) 16.48 ± 2.58* (− 32.2) 3.95 ± 1.15 (37.3) 1.13 ± 0.22 (0.0)
28.6 61.72 ± 5.19** (− 181.3) 13.78 ± 2.17 (23) 16.89 ± 1.04* (− 35.4) 3.98 ± 1.49 (36.8) 0.93 ± 0.13 (17.7)
1000 18.31 ± 1.00 (16.5) 13.9 ± 0.12 (22.3) 12.91 ± 0.67 (− 3.5) 3.7 ± 0.03 (41.3) 1.5 ± 0.04* (− 32.7)
2000 21.62 ± 1.96 (1.5) 12.8 ± 0.12 (28.5) 12.54 ± 0.41 (− 0.6) 3.4 ± 0.03 (46.0) 1.45 ± 0.04*(− 28.3)
3000 20.37 ± 1.51 (7.2) 16.0 ± 0.04 (10.6) 13.41 ± 0.47 (− 7.5) 4.2 ± 0.01 (33.3) 1.57 ± 0.02*(− 38.9)
  1. Data are expressed as mean ± SEM. n = 6.*p < 0.05 or **p < 0.001 when compared with control group. Values in parenthesis represent % change; (−) increase; (+) decrease. Control (Distilled Water, 10 ml/kg); Superoxide dismutase; GSH Reduced glutathione (μmol/mg protein), SOD Superoxide dismutase (μmol/min/mg protein), Catalase (μmol/ml/mg protein), GST Glutathione S-transferase (μmol/ml/mg protein), MDA Malondialdehyde (nmol/mg protein)