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Table 3 Effects of therapeutic and supra-therapeutic doses of CGV On Serum Biochemical Indices in Male Rats

From: Toxicological evaluation of therapeutic and supra-therapeutic doses of Cellgevity® on reproductive function and biochemical indices in Wistar rats

Treatment/ mg/kg UREA (mg/l) CREAT (mmol/l) CHOL (mmol/l) TG (mol/l) HDL (mmol/l) LDL (mmol/l) ALP (U/l) ALB (U/l) TP (U/l)
Control 10.55 ± 0.86 4.43 ± 0.76 1.64 ± 0.09 0.91 ± 0.16 0.57 ± 0.05 0.35 ± 0.04 18.90 ± 1.82 27.52 ± 1.81 13.71 ± 0.02
14.3 10.10 ± 0.21 (4.3) 4.11 ± 1.04 (7.2) 1.44 ± 0.22 (12.2) 0.89 ± 0.07 (2.1) 0.58 ± 0.02 (− 1.8) 0.33 ± 0.05 (5.7) 18.43 ± 2.02 (2.5) 26.25 ± 1.70 (4.6) 12.3 ± 0.47 (10.3)
28.6 10.90 ± 0.25 (3.3) 4.21 ± 1.03 (5.0) 1.38 ± 0.08 (15.9) 0.78 ± 0.11 (14.3) 0.52 ± 0.04 (8.8) 0.32 ± 0.03 (8.6) 18.06 ± 3.93 (4.4) 27.76 ± 2.05 (− 0.9) 11.47 ± 0.15 (16.3)
1000 9.58 ± 0.28 (9.2) 3.65 ± 0.99 (17.6) 1.57 ± 0.12 (4.3) 0.76 ± 0.07 (16.5) 0.55 ± 0.02 (3.5) 0.35 ± 0.02 (0) 18.32 ± 3.02 (3.1) 30.55 ± 3.70 (11) 13.3 ± 1.47 (3)
2000 9.50 ± 0.69 (10.0) 4.95 ± 2.13 (− 11.7) 1.57 ± 0.18 (4.3) 0.77 ± 0.11 (15.4) 0.59 ± 0.03 (− 3.5) 0.37 ± 0.07 (− 5.7) 17.66 ± 3.93 (6.6) 28.45 ± 3.05 (− 3.4) 5.47 ± 0.25* (60.1)
3000 9.90 ± 0.80 (10.1) 8.82 ± 1.75* (− 99.1) 1.61 ± 0.21 (1.8 s) 0.75 ± 0.07 (17.5) 0.56 ± 0.03 (1.8) 0.4 ± 0.08 (− 14.3) 18.75 ± 1.8 (0.8) 28.50 ± 3.12 (− 3.6) 5.87 ± 1.11* (57.2)
  1. Data are expressed as mean ± SEM. n = 6. *p < 0.05 or **p < 0.001 when compared with control group. Values in parenthesis represent % change; (−) increase; (+) decrease. Control (Distilled Water, 10 ml/kg). CREA Creatinine, CHOL cholesterol, TG Triglycerides, HDL High density lipoprotein, LDL Low density lipoprotein, ALP Alkaline phosphatase, ALB Albumin, TP total protein