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Table 3 Effects of therapeutic and supra-therapeutic doses of CGV On Serum Biochemical Indices in Male Rats

From: Toxicological evaluation of therapeutic and supra-therapeutic doses of Cellgevity® on reproductive function and biochemical indices in Wistar rats

Treatment/ mg/kg

UREA (mg/l)

CREAT (mmol/l)

CHOL (mmol/l)

TG (mol/l)

HDL (mmol/l)

LDL (mmol/l)

ALP (U/l)

ALB (U/l)

TP (U/l)

Control

10.55 ± 0.86

4.43 ± 0.76

1.64 ± 0.09

0.91 ± 0.16

0.57 ± 0.05

0.35 ± 0.04

18.90 ± 1.82

27.52 ± 1.81

13.71 ± 0.02

14.3

10.10 ± 0.21 (4.3)

4.11 ± 1.04 (7.2)

1.44 ± 0.22 (12.2)

0.89 ± 0.07 (2.1)

0.58 ± 0.02 (− 1.8)

0.33 ± 0.05 (5.7)

18.43 ± 2.02 (2.5)

26.25 ± 1.70 (4.6)

12.3 ± 0.47 (10.3)

28.6

10.90 ± 0.25 (3.3)

4.21 ± 1.03 (5.0)

1.38 ± 0.08 (15.9)

0.78 ± 0.11 (14.3)

0.52 ± 0.04 (8.8)

0.32 ± 0.03 (8.6)

18.06 ± 3.93 (4.4)

27.76 ± 2.05 (− 0.9)

11.47 ± 0.15 (16.3)

1000

9.58 ± 0.28 (9.2)

3.65 ± 0.99 (17.6)

1.57 ± 0.12 (4.3)

0.76 ± 0.07 (16.5)

0.55 ± 0.02 (3.5)

0.35 ± 0.02 (0)

18.32 ± 3.02 (3.1)

30.55 ± 3.70 (11)

13.3 ± 1.47 (3)

2000

9.50 ± 0.69 (10.0)

4.95 ± 2.13 (− 11.7)

1.57 ± 0.18 (4.3)

0.77 ± 0.11 (15.4)

0.59 ± 0.03 (− 3.5)

0.37 ± 0.07 (− 5.7)

17.66 ± 3.93 (6.6)

28.45 ± 3.05 (− 3.4)

5.47 ± 0.25* (60.1)

3000

9.90 ± 0.80 (10.1)

8.82 ± 1.75* (− 99.1)

1.61 ± 0.21 (1.8 s)

0.75 ± 0.07 (17.5)

0.56 ± 0.03 (1.8)

0.4 ± 0.08 (− 14.3)

18.75 ± 1.8 (0.8)

28.50 ± 3.12 (− 3.6)

5.87 ± 1.11* (57.2)

  1. Data are expressed as mean ± SEM. n = 6. *p < 0.05 or **p < 0.001 when compared with control group. Values in parenthesis represent % change; (−) increase; (+) decrease. Control (Distilled Water, 10 ml/kg). CREA Creatinine, CHOL cholesterol, TG Triglycerides, HDL High density lipoprotein, LDL Low density lipoprotein, ALP Alkaline phosphatase, ALB Albumin, TP total protein