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Table 4 Effects of therapeutic and supra-therapeutic doses of CGV On Serum Biochemical Parameters in Female Rats

From: Toxicological evaluation of therapeutic and supra-therapeutic doses of Cellgevity® on reproductive function and biochemical indices in Wistar rats

Treatment/ mg/kg UREA (mg/dl) CREA (mmol/l) CHOL (mmol/l) TG (mol/l) HDL (mmol/l) LDL (mmol/l) ALP (U/l) ALB (U/l) TP (U/l)
Control 9.47 ± 0.52 1.33 ± 0.40 1.31 ± 0.08 0.86 ± 0.06 0.58 ± 0.01 0.26 ± 0.04 16.18 ± 1.59 27.78 ± 1.60 9.72 ± 1.19
14.3 9.55 ± 0.42 (− 0.8) 1.29 ± 0.21 (3.0) 1.36 ± 0.09 (− 3.8) 0.87 ± 0.02 (− 1.1) 0.55 ± 0.02 (5.2) 0.27 ± 0.04 (− 3.8) 16.22 ± 1.78 (0.2) 31.03 ± 1.54 (− 12.7) 9.93 ± 1.01 (− 2.16)
28.6 9.16 ± 0.55 (−0.8) 1.13 ± 1.31 (15) 1.32 ± 0.02 (0.8) 0.77 ± 0.03 (10.5) 0.58 ± 0.03 (0) 0.28 ± 0.02 (− 7.7) 16.30 ± 1.29 (− 0.7) 30.44 ± 1.63 (− 9.6) 10.46 ± 1.22 (− 7.6)
1000 9.65 ± 0.32 (− 2.17) 2.29 ± 0.27* (72.18) 1.46 ± 0.11 (− 11.5) 0.68 ± 0.03 (20.9) 0.56 ± 0.01 (3.4) 0.29 ± 0.03 (− 11.5) 16.22 ± 2.80 (− 0.2) 33.43 ± 2.54 (20) 10.32 ± 1.21 ()
2000 9.25 ± 0.78 (2.3) 2.13 ± 1.32* (60.2) 1.32 ± 0.03 (− 0.8) 0.69 ± 0.04 (19.8) 0.59 ± 0.02 (− 1.7) 0.27 ± 0.03 (− 3.8) 16.30 ± 2.29 (− 0.7) 30.25 ± 3.63 (− 8.9) 11.36 ± 1.82 (− 6.2)
3000 9.90 ± 0.21 (− 4.5) 2.99 ± 2.07* (− 124.8) 1.57 ± 0.09 (− 19.8) 0.72 ± 0.03 (16.3) 0.57 ± 0.01 (1.7) 0.35 ± 0.03* (34.6) 15.42 ± 1.44 (4.7) 29.98 ± 3.02 (− 7.9) 11.08 ± 1.25 (− 14.0)
  1. Data are expressed as mean ± SEM. n = 6.*p < 0.05 or **p < 0.001 when compared with control group. Values in parenthesis represent % change; (−) increase; (+) decrease. Control (Distilled Water, 10 ml/kg). CREA Creatinine, CHOL cholesterol, TG Triglycerides, HDL High density lipoprotein, LDL Low density lipoprotein, ALP Alkaline phosphatase, ALB Albumin, TP total protein