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Table 1 HSP protects ROS -mediated toxicity induced by nZnO

From: Hesperidin alleviates zinc oxide nanoparticle induced hepatotoxicity and oxidative stress

EXPERIMENTAL GROUPS

Parameters

Control (I)

n ZnO (II)

HSP (III)

HSP + nZnO (IV)

GSH (mmol/mg prot)

1.08 ± 0.02

0.97. ±0.01*

1.12 ± 0.06

1.47 ± 0.04**

CAT (IU/mg prot)

1.95 ± 0.11

0.91 ± 0.14*

1.82 ± 0.11

1.45 ± 0.14**

GPx (U/mg prot)

1.13 ± 0.01

0.54 ± 0.07*

1.11 ± 0.05

0.95 ± 0.02**

  1. All values are mean ± SEM, n = 6; * I vs. II (*P < 0.05). II vs. IV (**P < 0.05)
  2. GSH: *t = 6.133; *P 0.002, DF = 5,11: **t = 4.45; **P 0.007, DF = 5,11/ CAT: *t = 49.2; *P 0.001, DF = 1,11: **t = 41.6; **P 0.001, DF = 1,11/ GPx: *t = 33.13; *P 0.002, DF = 1,11: **t = 43.74; **P 0.001, DF = 1,11
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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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