Participant variable | Efavirenz concentration | ||||
---|---|---|---|---|---|
< 1 μg/mL n (%) | 1 - 4 μg/mL n (%) | >  4 μg/mL n (%) | p value | ||
Sex | Male | 11(12.9%) | 52(61.2%) | 22(25.9%) | 0.064 |
Females | 13(21.7%) | 25(41.7%) | 22(36.7%) | ||
Age group (years) | 5–10 | 7(11.1%) | 41(65.1%) | 15(23.8%) | 0.037 |
11–15 | 17(20.7%) | 36(43.9%) | 29(35.4%) | ||
Orphan status | Not orphaned | 11 (13.4%) | 53 (64.6%) | 18 (22.0%) | 0.006 |
Orphaned | 13 (20.6%) | 24 (38.1%) | 26 (41.3%) | ||
BMI-for-age percentiles | <5th percentile | 5 (10.9%) | 18 (39.1%) | 23 (50.0%) | 0.011 |
5-85th percentile | 19 (19.4%) | 58 (59.2%) | 21 (21.4%) | ||
>85th percentile | 0 | 1 (100%) | 0 | ||
Weight for age (WAZ) | Normal weight | 15(16.3%) | 53(57.6%) | 24(26.1%) | 0.341 |
Moderately undernourished | 6(18.8%) | 12(37.5%) | 14(43.8%) | ||
Severely undernourished | 3(14.3%) | 12(57.1%) | 6(28.6%) | ||
Height for age (HAZ) | Normal height | 17(18.1%) | 49(52.1%) | 28(29.8%) | 0.906 |
Moderately stunted | 5(13.2%) | 20(52.6%) | 13(34.2%) | ||
Severely stunted | 2(15.2%) | 8(61.5%) | 3(23.1%) | ||
MUAC | Normal nutrition | 16(17.2%) | 54(58.1%) | 23(24.7%) | 0.690 |
Moderate malnutrition | 6(12.8%) | 21(44.7%) | 20(42.6%) | ||
Severe malnutrition | 2(50.0%) | 2(50.0%) | 0(0.0%) | ||
CD4 cell count (cells/μL) | > 350 cells | 17 (13.8%) | 68(55.3%) | 38(30.9%) | 0.108 |
< 350 cells | 7(31.8%) | 9(40.9%) | 6(27.3%) | ||
Viral load (copies/mL) | < 400 copies | 7(6.7%) | 61(58.1%) | 37(35.2%) | 0.000 |
400–1000 copies | 1(33.3%) | 1(33.3%) | 1(33.3%) | ||
> 1000 copies | 16(43.2%) | 15(40.5%) | 6(16.2%) | ||
Concurrent Medication | No | 15 (14.9%) | 51 (50.5%) | 35 (34.7%) | 0.218 |
Yes | 9 (20.5%) | 26 (59.1%) | 9 (20.5%) |