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Table 4 Clinical variables associated with hospital mortality in patients with organophosphate and carbamate poisoning analyzed by multivariate Cox regression (N = 6832)

From: One-year mortality among hospital survivors of cholinesterase inhibitor poisoning based on Taiwan National Health Insurance Research Database from 2003 to 2012

Parameter Univariate analysis P value Multivariate analysis P value
HR (95% CI) HR (95% CI)
Age 1.022 (1.018–1.026) < 0.0001 1.020 (1.015–1.024) < 0.0001
Female Sex 1.148 (0.999–1.318) 0.0506   
Diabetes 1.076 (0.885–1.306) 0.4635   
Hypertension 0.629 (0.497–0.794) < 0.0001 0.615 (0.485–0.779) 0.0001
Coronary artery disease 0.582 (0.360–0.941) 0.0273 0.485 (0.300–0.785) 0.0751
Cerebrovascular accident 1.179 (0.828–1.679) 0.3607   
Chronic renal failure 2.634 (1.690–4.105) < 0.0001 1.449 (0.893–2.351) 0.1330
Chronic obstructive pulmonary disease 0.875 (0.534–1.436) 0.5980   
Asthma 0.544 (0.175–1.688) 0.2920   
Liver failure 2.693 (1.486–4.882) 0.0011 2.348 (1.293–4.264) 0.0050
Atropine 2.406 (2.054–2.818) < 0.0001 1.951 (1.628–2.337) < 0.0001
Pralidoxime 1.184 (1.032–1.359) 0.0161 0.591 (0.506–0.691) < 0.0001
Hemodialysis 2.520 (1.929–3.291) < 0.0001 1.454 (1.087–1.946) 0.0117
Pneumonia 0.754 (0.600–0.947) 0.0154 0.480 (0.382–0.603) < 0.0001
Mechanical ventilation 5.160 (4.426–6.014) < 0.0001 4.684 (3.976–5.517) < 0.0001
  1. CI, Confidence interval; Data are presented as mean ± SD or N (%)