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Table 3 Percentage of patients with adverse effects observed in the COMPARZ study

From: Pazopanib: Evidence review and clinical practice in the management of advanced renal cell carcinoma

ADVERSE EFFECT

PAZOPANIB

SUNITINIB

Fatigue

 Any grade

50%

63%

 Grade 3–4

10%

17%

Hand-foot syndrome

 Any grade

29%

50%

 Grade 3–4

6%

11%

Stomatitis

 Any grade

14%

27%

ALTb

60%

43%

Fatal AEas

2%

3%

Fatal treatment-related AEs

3 cases

8 cases

  1. aAE: adverse events; bALT: alanine aminotransferase