a) CEM cells
|
---|
|
Cellular accumulation ration (CAR)
| | |
---|
Sample
|
1
|
2
|
3
|
4
|
5
|
Average
|
STDEV
|
p value
|
CEM SQV
|
1.5
|
1.3
|
1.8
|
1.6
|
1.4
|
1.5
|
0.2
| |
CEM SQV+P
|
1.5
|
1.6
|
1.5
|
1.7
|
1.4
|
1.5
|
0.1
|
p = 0.97
|
CEM SQV 05
|
2.2
|
1.8
|
1.8
|
1.9
|
2.0
|
1.9
|
0.2
|
p = 0.03
|
CEM SQV 06
|
2.2
|
1.5
|
2.1
|
2.0
|
1.7
|
1.9
|
0.3
|
p = 0.04
|
CEM SQV 07
|
2.1
|
1.4
|
1.8
|
2.2
|
1.6
|
1.8
|
0.3
|
p = 0.12
|
CEM SQV 09
|
1.9
|
1.6
|
1.9
|
2.3
|
1.7
|
1.9
|
0.3
|
p = 0.04
|
CEM SQV 13
|
1.8
|
1.6
|
1.5
|
2.1
|
2.4
|
1.9
|
0.4
|
p = 0.10
|
b) CEM VBL cells
|
|
Cellular accumulation ration (CAR)
|
Sample
|
1
|
2
|
3
|
4
|
5
|
Average
|
STDEV
|
p value
|
VBL SQV
|
1.0
|
1.1
|
1.3
|
1.4
|
1.5
|
1.3
|
0.2
| |
VBL SQV+P
|
1.2
|
1.5
|
1.4
|
1.2
|
1.4
|
1.3
|
0.1
|
p = 0.48
|
VBL SQV 05
|
1.0
|
0.9
|
1.3
|
1.4
|
1.7
|
1.3
|
0.3
|
p = 0.99
|
VBL SQV 06
|
1.0
|
1.1
|
1.5
|
1.6
|
1.9
|
1.4
|
0.4
|
p = 0.49
|
VBL SQV 07
|
0.8
|
1.0
|
1.2
|
1.5
|
1.7
|
1.2
|
0.4
|
p = 0.93
|
VBL SQV 09
|
1.1
|
0.9
|
1.4
|
1.5
|
1.3
|
1.2
|
0.2
|
p = 0.92
|
VBL SQV 13
|
1.0
|
0.8
|
1.4
|
1.5
|
1.9
|
1.3
|
0.4
|
p = 0.80
|
- P = Excipients for SQV 13 sample