Table 3 Factors associated with drug-drug interaction using logistic regression (n = 1044)
Variable | Univariate Regression | Multivariate Regression | ||
|---|---|---|---|---|
OR (95%CI) | p-value | OR (95%CI) | p-value | |
Prescribed drugs | ||||
≤ 6 | Reference | Reference | ||
> 6 | 2.172 (1.590–2.968) | < 0.001 | 2.870 (2.011–4.095) | < 0.001 |
Age | ||||
≤ 75 | Reference | 0.106 | Reference | |
> 75 | 0.748 (0.526–1.064) | 0.588 (0.386–0.897) | < 0.05 | |
Duration of stay | ||||
≤ 3 | Reference | < 0.001 | Reference | |
> 3 | 0.622 (0.472–0.820) | 0.868 (0.626–1.204) | 0.397 | |
Gender | ||||
Male | Reference | 0.250 | Reference | |
Female | 0.853 (0.650–1.119) | 0.820 (0.595–1.129) | 0.224 | |
Chronic illness | ||||
Myocardial infarction | 0.018 (0.005–0.058) | < 0.001 | 0.012 (0.003–0.040) | < 0.001 |
Cerebrovascular accident | 0.192 (0.080–0.463) | < 0.001 | 0.147 (0.059–0.367) | < 0.001 |
Acute coronary syndrome | 0.043 (0.011–0.162) | < 0.001 | 0.037 (0.009–0.142) | < 0.001 |
Heart failure | 0.384 (0.157–0.936) | < 0.05 | 0.265 (0.105–0.673) | < 0.05 |