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Table 3 Factors associated with drug-drug interaction using logistic regression (n = 1044)

From: Epidemiology of potential drug-drug interactions in elderly population admitted to critical care units of Peshawar, Pakistan

Variable Univariate Regression Multivariate Regression
OR (95%CI) p-value OR (95%CI) p-value
Prescribed drugs
 ≤ 6 Reference   Reference  
 > 6 2.172 (1.590–2.968) < 0.001 2.870 (2.011–4.095) < 0.001
Age
 ≤ 75 Reference 0.106 Reference  
 > 75 0.748 (0.526–1.064)   0.588 (0.386–0.897) < 0.05
Duration of stay
 ≤ 3 Reference < 0.001 Reference  
 > 3 0.622 (0.472–0.820)   0.868 (0.626–1.204) 0.397
Gender
 Male Reference 0.250 Reference  
 Female 0.853 (0.650–1.119)   0.820 (0.595–1.129) 0.224
Chronic illness
 Myocardial infarction 0.018 (0.005–0.058) < 0.001 0.012 (0.003–0.040) < 0.001
 Cerebrovascular accident 0.192 (0.080–0.463) < 0.001 0.147 (0.059–0.367) < 0.001
 Acute coronary syndrome 0.043 (0.011–0.162) < 0.001 0.037 (0.009–0.142) < 0.001
 Heart failure 0.384 (0.157–0.936) < 0.05 0.265 (0.105–0.673) < 0.05
  1. CI Confidence interval