Fig. 4
From: Impact of continued administration of tolvaptan on cirrhotic patients with ascites
Changes in biochemical parameters in blood after 1 year of tolvaptan. a) Serum levels of albumin, b) total bilirubin, c) PT%, d) PT/INR, e) creatinine, f) ammonia, g) the modified CP score, and h) MELD score. Albumin levels were significantly increased (a, p < 0.01), whereas total bilirubin (b, p = 0.06), PT/INR (d, p = 0.02), and ammonia (f, p < 0.01) were reduced after 1 year of tolvaptan treatment. The modified CP score was significantly improved (g, p < 0.01). The MELD score was also reduced, however, it not significantly (h, p = 0.13). PT, prothrombin time; INR, international normalized ratio; CP, Child- Pugh; MELD, model for end-stage liver disease