Skip to main content

Table 1 Demographic Characteristics

From: First-in-human study assessing safety, tolerability, and pharmacokinetics of 2-hydroxybenzylamine acetate, a selective dicarbonyl electrophile scavenger, in healthy volunteers

 

2-Hydroxybenzylamine acetate dose

 

50 mg

100 mg

200 mg

330 mg

550 mg

825 mg

Total

Volunteers (n)

3

3

3

3

3

3

18

Sex: female [n (%)]

2 (66.7)

1 (33.3)

0 (0)

3 (100)

1 (33.3)

2 (66.7)

9 (50.0)

Age (y)

25.7 ± 2.1

32.7 ± 6.4

27.7 ± 5.7

26.3 ± 4.0

28.0 ± 6.0

23.0 ± 2.6

27.2 ± 5.0

Height (cm)

174.3 ± 7.6

184.6 ± 11.7

174.2 ± 4.0

165.7 ± 6.8

175.7 ± 17.8

160.4 ± 5.6

172.5 ± 11.6

Weight (kg)

60.7 ± 2.1

95.0 ± 37.0

83.3 ± 30.6

60.0 ± 8.0

87.7 ± 33.8

68.3 ± 14.2

75.8 ± 25.1

BMI (kg/m2)

20.1 ± 2.3

27.3 ± 7.8

27.2 ± 8.8

21.8 ± 1.3

27.5 ± 5.0

26.4 ± 3.8

25.0 ± 5.6

Race

 Hawaiian/Pacific Islander

0 (0)

0 (0)

0 (0)

0 (0)

1 (33.3)

0 (0)

1 (5.5)

 White

3 (100)

3 (100)

3 (100)

3 (100)

2 (66.7)

3 (100)

17 (94.4)

Ethnicity

 Hispanic/Latino

0 (0)

0 (0)

0 (0)

0 (0)

1 (33.3)

0 (0)

1 (5.5)

 Not Hispanic/Latino

3 (100)

3 (100)

3 (100)

3 (100)

2 (66.7)

3 (100)

17 (94.4)

  1. Data are presented as means ± SD unless otherwise noted