Skip to main content

Table 1 Demographic Characteristics

From: First-in-human study assessing safety, tolerability, and pharmacokinetics of 2-hydroxybenzylamine acetate, a selective dicarbonyl electrophile scavenger, in healthy volunteers

  2-Hydroxybenzylamine acetate dose  
50 mg 100 mg 200 mg 330 mg 550 mg 825 mg Total
Volunteers (n) 3 3 3 3 3 3 18
Sex: female [n (%)] 2 (66.7) 1 (33.3) 0 (0) 3 (100) 1 (33.3) 2 (66.7) 9 (50.0)
Age (y) 25.7 ± 2.1 32.7 ± 6.4 27.7 ± 5.7 26.3 ± 4.0 28.0 ± 6.0 23.0 ± 2.6 27.2 ± 5.0
Height (cm) 174.3 ± 7.6 184.6 ± 11.7 174.2 ± 4.0 165.7 ± 6.8 175.7 ± 17.8 160.4 ± 5.6 172.5 ± 11.6
Weight (kg) 60.7 ± 2.1 95.0 ± 37.0 83.3 ± 30.6 60.0 ± 8.0 87.7 ± 33.8 68.3 ± 14.2 75.8 ± 25.1
BMI (kg/m2) 20.1 ± 2.3 27.3 ± 7.8 27.2 ± 8.8 21.8 ± 1.3 27.5 ± 5.0 26.4 ± 3.8 25.0 ± 5.6
Race
 Hawaiian/Pacific Islander 0 (0) 0 (0) 0 (0) 0 (0) 1 (33.3) 0 (0) 1 (5.5)
 White 3 (100) 3 (100) 3 (100) 3 (100) 2 (66.7) 3 (100) 17 (94.4)
Ethnicity
 Hispanic/Latino 0 (0) 0 (0) 0 (0) 0 (0) 1 (33.3) 0 (0) 1 (5.5)
 Not Hispanic/Latino 3 (100) 3 (100) 3 (100) 3 (100) 2 (66.7) 3 (100) 17 (94.4)
  1. Data are presented as means ± SD unless otherwise noted