Fig. 1
From: Atypical antipsychotics induce human osteoblasts apoptosis via Wnt/β-catenin signaling
Inhibition of OB cells viability after APs treatment. a, OB cell viability was examined by CCK-8 assay after exposured to olanzapine (0.1%DMSO, 10, 20, 40, 80 or 120 μM), risperidone (0.1%DMSO, 10, 20, 40, 80 or 120μM), amisulpride (0.1%DMSO, 10, 20, 40, 80 or 120μM) or aripiprazole (0.1%DMSO, 2.5, 5, 10, 20 or 40 μM) at 12h, 24h or 48h (a, c, e, g). Bar graph indicated the IC-50 values of olanzapine, risperidone, amisulpride, aripiprazole in 1640 mediuM at 12, 24 and 48 hours (b, d, f, h). The data were calculated with GraphPad Prism. *P < 0.05; **P < 0.01