Table 2 The Gene Ontology (GO)-Biological Process (BP) and KEGG pathway analyses of genes of the three modules from the protein-protein interaction network
Module | Category | Term | Count | P Value | Genes |
|---|---|---|---|---|---|
Module 1 | GO_BP | GO:0007608~sensory perception of smell | 14 | 2.41E-16 | OLFR872/OLFR323/OLFR734/OLFR308/OLFR646/OLFR555/OLFR316/OLFR384/OLFR804/OLFR171/OLFR365/OLFR1392/OLFR790/OLFR1090 |
GO_BP | GO:0007186~G-protein coupled receptor signaling pathway | 14 | 4.50E-14 | OLFR872/OLFR323/OLFR734/OLFR308/OLFR646/OLFR555/OLFR316/OLFR384/OLFR804/OLFR171/OLFR365/OLFR1392/OLFR790/OLFR1090 | |
GO_BP | GO:0050907~detection of chemical stimulus involved in sensory perception | 3 | 9.28E-03 | OLFR734/OLFR384/OLFR365 | |
KEGG_PATHWAY | mmu04740:Olfactory transduction | 12 | 3.84E-10 | OLFR872/OLFR323/OLFR734/OLFR308/OLFR646/OLFR555/OLFR384/OLFR171/OLFR365/OLFR1392/OLFR790/OLFR1090 | |
Module 2 | GO_BP | GO:0007165~signal transduction | 5 | 6.82E-04 | P2RY13/CCR3/S1PR4/ANXA1/CXCR2 |
GO_BP | GO:0007186~G-protein coupled receptor signaling pathway | 5 | 2.19E-03 | P2RY13/CCR3/NPW/S1PR4/CXCR2 | |
GO_BP | GO:0006954~inflammatory response | 3 | 7.11E-03 | CCR3/ANXA1/GAL | |
GO_BP | GO:0007631~feeding behavior | 2 | 1.31E-02 | NPW/GAL | |
GO_BP | GO:0006935~chemotaxis | 2 | 4.48E-02 | CCR3/CXCR2 | |
GO_BP | GO:0045766~positive regulation of angiogenesis | 2 | 4.59E-02 | CCR3/CXCR2 | |
Module 3 | GO_BP | GO:0006412~translation | 3 | 2.86E-03 | RPL35A/RPL18A/RPL28 |
GO_BP | GO:0006364~rRNA processing | 2 | 2.76E-02 | RPL35A/EXOSC3 | |
KEGG_PATHWAY | mmu03010:Ribosome | 3 | 2.05E-03 | RPL35A/RPL18A/RPL28 |