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Table 2 Effects of 100 mg/kg and 200 mg/kg of CNBP on Liver functions of SD rats (n = 6)

From: Gastroprotective activity of a novel Schiff base derived dibromo substituted compound against ethanol-induced acute gastric lesions in rats

Animal groups Liver function test
Total protein (g/l) Albumin (g/l) Globulin (g/l) TB (μM/l) CB (μM/l) AP (IU/l) ALT (IU/l) AST (IU/L) GGT (IU/L)
Control (10% Tween 20) 60.33 ± 0.27 40.33 ± 0.27 22.00 ± .0.47 1.83 ± 0.14 0.90 ± 0.15 119.00 ± 2.94 53.67 ± 1.19 126.67 ± 2.13 1.00 ± 0.00
CNBP(100 mg/kg) 59.33 ± 0.72 37.33 ± 0.54 22.00 ± 0.47 2.00 ± 0.00 0.95 ± 0.19 137.67 ± 0.27 54.67 ± 1.09 122.33 ± 3.60 1.67 ± 0.02
CNBP(200 mg/kg) 60.33 ± 1.36 38.67 ± 1.19 21.67 ± 0.54 2.00 ± 0.00 0.89 ± 0.21 143.00 ± 3.68 68.33 ± 3.31 151.00 ± 0.82 1.67 ± 0.27
  1. TB Total bilirubin, CB Conjugated bilirubin, AP Alkaline phosphatase, ALT Alanine transaminase, AST Aspartate transaminase, GGT G-Glutaml transferase
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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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