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Table 2 Main features of the studies

From: Dipeptidyl peptidase 4 (DPP-4) inhibitors and cardiovascular outcomes in patients with type 2 diabetes mellitus (T2DM): a systematic review and meta-analysis

Studies Type of study Time period of patients’ enrollment Total no of patients assigned to DPP-4 inhibitors (n) Total no of patients assigned to control group (n)
Gantz2017 [7] RCT 2012–2017 2092 2100
Green2015 [8] RCT 2008–2015 7332 7339
Park2015 [9] OS 2007–2011 1866 5179
Scirica2013 [10] RCT 2010–2011 8280 8212
Shih2016 [11] OS 2009–2013 53,208 53,208
Wang2015 [12] OS 2009–2011 547 2735
White2013 [13] RCT 2009–2013 2701 2679
Total no of patients (n)    76,026 81,452
  1. Abbreviations: RCT Randomized controlled trials, OS Observational studies, DPP-4 dipeptidyl peptidase 4