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Table 3 Most commonly implicated drugs in Emergency Department (ED) visits for adverse drug events (ADEs)

From: Characterization and preventability of adverse drug events as cause of emergency department visits: a prospective 1-year observational study

  ADE-related
ED visitsa,b
Serious ADE-related ED visitsa,b Preventable ADE-related ED visitsa,b
ATC 5th level Drug No. of Cases (%) No. of Cases (%) No. of Cases (%)
J01CR02 Amoxicillin/clavulanic acid 82 (14.3) 13 (7.6) 1 (1.4)
M01AE03 Ketoprofen 62 (10.9) 7 (4.1) 2 (2.8)
J01DD04 Ceftriaxone 38 (6.6) 8 (4.7) 1 (1.4)
J01CA04 Amoxicillin 28 (4.9) 4 (2.4) 1 (1.4)
B01AC06 Acetylsalicylic acid 27 (4.7) 9 (5.3) 4 (5.6)
J01MA12 Levofloxacin 17 (3.0) 5 (2.9) 1 (1.4)
M01AB05 Diclofenac 16 (2.9) 1 (0.6)
M01AX17 Nimesulide 13 (2.3) 2 (1.2) 1 (1.4)
M01AE01 Ibuprofen 15 (2.6) 2 (1.2)
N05BA06 Lorazepam 10 (1.7) 7 (4.1) 9 (12.7)
M01AH05 Etoricoxib 10 (1.7) 3 (1.8) 2 (2.8)
A10BA02 Metformin 9 (1.6) 6 (3.5) 3 (4.2)
H02AB01 Betamethasone 9 (1.6) 1 (0.6) 1 (1.4)
B01AA03 Warfarin 8 (1.4) 5 (2.9) 4 (5.6)
J01MA02 Ciprofloxacin 8 (1.4)
C03CA01 Furosemide 7 (1.2) 6 (3.5) 2 (2.8)
C09AA05 Ramipril 7 (1.2) 6 (3.5)
N02BE01 Paracetamol 6 (1.0) 2 (2.8)
N02BE51 Paracetamol, combinations excl. Psycholeptics 6 (1.0)
N03AF01 Carbamazepine 6 (1.0) 4 (2.4) 2 (2.8)
B01AA07 Acenocoumarol 6 (1.0) 4 (2.4) 2 (2.8)
M03BX05 Thiocolchicoside 6 (1.0) 1 (0.6)
C01AA05 Digoxin 6 (1.0) 6 (3.5) 2 (2.8)
N02BA51 Acetylsalicylic acid, combinations excl. psycholeptics 6 (1.0)
  1. ATC (5th level), Anatomical Therapeutic Chemical classification (5th level)
  2. aDrugs implicated in > 5 cases were considered
  3. bThe sum of suspected drugs is higher than the total number of cases, since a single patient could have used multiple drugs