Variables | Deatha n = 23 | Survivala n = 54 | OR (95% CI) | p |
---|---|---|---|---|
Demographic parameters | ||||
Age, year | 63.0 (18.5) | 61.8 (16.5) | 0.644 | |
Female gender | 9 (39.1%) | 16 (29.6%) | 1.53 (0.55–4.24) | 0.415 |
Comorbidities | ||||
Hepatic dysfunction | 0 (0.0%) | 2 (3.7%) | 0.69 (0.60–0.81) | 1.000 |
Renal insufficiency | 1 (4.3%) | 6 (11.1%) | 0.36 (0.41–3.21) | 0.667 |
Chronic pulmonary disease | 6 (26.1%) | 15 (27.8%) | 0.92 (0.30–2.78) | 0.879 |
Heart disease | 2 (8.7%) | 11 (20.4%) | 0.37 (0.08–1.83) | 0.323 |
Diabetes mellitus | 2 (8.7%) | 2 (3.7%) | 2.48 (0.33–18.75) | 0.578 |
Immune compromise | 2 (8.7%) | 3 (5.6%) | 1.62 (0.25–10.40) | 0.632 |
Malignancy | 2 (8.7%) | 5 (9.3%) | 0.93 (0.17–5.20) | 1.000 |
Hypoproteinemia | 0 (0.0%) | 2 (3.7%) | 0.69 (0.60–0.81) | 1.000 |
Surgery | 5 (21.7%) | 11 (20.4%) | 1.09 (0.33–3.58) | 1.000 |
Clinical conditions | ||||
CURB65 score, mean ± SD | 2.7 (1.1) | 1.7 (0.8) | 0.001 | |
Mechanical ventilation | 21 (91.3%) | 27 (50.0%) | 10.5 (2.24–49.24) | 0.001 |
Albumin | 32.2 (4.9) | 32.1 (4.3) | 0.916 | |
Microbiology | ||||
Bacteremia | 5 (21.7%) | 2 (3.7%) | 7.22 (1.29–40.54) | 0.022 |
Tigecycline resistance | 16 (69.6%) | 19 (35.2%) | 0.24 (0.08–0.68) | 0.006 |
Airway eradication of MDRAB | 5 (27.8%) | 19 (48.7%) | 0.40 (0.12–1.35) | 0.137 |
Tigecycline treatment | ||||
Duration, days | 10.0 (6.6) | 12.4 (5.8) | 0.014 | |
Combination therapy | ||||
With sulbactam | 19 (82.6%) | 45 (83.3%) | 0.95 (0.26–3.47) | 1.000 |
With carbapenems | 1 (4.3%) | 3 (5.6%) | 0.77 (0.08–7.84) | 1.000 |
With amikacin | 1 (4.3%) | 2 (3.8%) | 1.16 (0.10–13.46) | 1.000 |
With fluoroquinolones | 1 (4.3%) | 3 (5.6%) | 0.77 (0.08–7.84) | 1.000 |
Delayed tigecycline treatment | 6 (26.1%) | 15 (27.8%) | 0.92 (0.30–2.77) | 0.879 |