From: Apigenin and hesperidin augment the toxic effect of doxorubicin against HepG2 cells
Concentration [μM] | Control | DOX | A | H | HAGL | B | BAGL | C | R | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 200 | 100 | 50 | 200 | 100 | 50 | 200 | 100 | 50 | 200 | 100 | 50 | 200 | 100 | 50 | 200 | 100 | 50 | 200 | 100 | 50 | ||
 | Mean ± SD % | ||||||||||||||||||||||
 | 100.04 ± 2.99 |  |  |  |  |  |  |  |  | ||||||||||||||
Compound alone |  | 67.77 ± 2.44 | 45.66 ± 3.44* | 50.55 ± 2.60* | 67.64 ± 3.85* | 66.55 ± 3.87* | 75.85 ± 3.54* | 82.65 ± 3.32* | 81.64 ± 1.73* | 97.24 ± 2.50 | 99.67 ± 3.45 | 81.50 ± 2.60* | 87.74 ± 4.41* | 90.52 ± 3.35* | 74.04 ± 3.21* | 77.82 ± 7.44* | 81.73 ± 5.34* | 100.81 ± 4.07 | 101.05 ± 2.13 | 99.87 ± 6.12 | 98.35 ± 7.08 | 99.13 ± 1.91 | 106.17 ± 9.50 |
Compound + DOX |  |  | 32.75 ± 1.15♦ | 35.62 ± 0.73♦ | 52.31 ± 0.47♦ | 50.85 ± 2.28♦ | 62,23 ± 5.32♦ | 63.88 ± 3.55♦ | 78.96 ± 2.04 | 87.53 ± 3.97♦ | 86.55 ± 5.38♦ | 79.84 ± 2.65 | 80.79 ± 5.26 | 80.99 ± 3.46♦ | 68.79 ± 1.59 | 69.71 ± 3.20 | 69,11 ± 5.54 | 82.23 ± 5.08♦ | 76.77 ± 1.50♦ | 79.64 ± 2.18♦ | 73.02 ± 2.15♦ | 80.26 ± 1.75♦ | 87.03 ± 3.43♦ |