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Table 1 Baseline characteristics of patients treated with amikacin

From: Safety and effectiveness of low-dose amikacin in nontuberculous mycobacterial pulmonary disease treated in Toronto, Canada

Baseline characteristics

N = 107 (%)

Sex, Female

70 (65.4)

Age (Years), Mean (SD)

58.3 (14.9)

Race

 Caucasian

72 (67.3)

 South Asian

4 (3.7)

 East Asian

28 (26.2)

 African

3 (2.8)

Comorbidities

 COPD/Emphysema

19 (17.7)

 Previous TB

13 (12.1)

 Cystic fibrosis

6 (5.6)

 Asthma

5 (4.7)

 Autoimmune disorders

5 (4.7)

 Alpha 1 antitrypsin deficiency

2 (1.9)

 Sarcoidosis

2 (1.9)

 ABPA

2 (1.9)

 Allogenic stem cell transplant

2 (1.9)

 HIV infection

1 (0.9)

Species

 MACa

69 (64.5)

 M. abscessus

21 (19.6)

 M. xenopi

11 (10.3)

 MAC and M. xenopi

4 (3.7)

 M. shimodei

1 (0.9)

 M. fortuitum

1 (0.9)

AFB smear positive ever

100 (93.5)

Aspergillus isolation

39 (36.4)

CT pattern

 Nodular bronchiectatic

55 (51.4)

 Fibrocavitary

40 (37.4)

 Random nodules

2 (1.9)

 Consolidation

0 (0)

 Unclassifiable

10 (9.3)

Cavity

66 (61.7)

Indication for treatment

 First line

39 (36.4)

 Second line

68 (63.6)

  1. SD Standard deviation, COPD Chronic Obstructive Pulmonary Disease, TB Tuberculosis, SLE Systemic Lupus Erythematous, ABPA Allergic Bronchopulmonary Aspergillosis, HIV Human Immunodeficiency Virus, MAC Mycobacterium avium complex, AFB Acid Fast Bacilli, CT Computed Tomography
  2. aFive patients had Clarithromycin resistant MAC; MAC isolates were not identified to the species level prior to 2010, and so are reported as MAC herein