Table 4 Patient characteristics and their association with sputum culture conversion
|  | Sputum culture conversion N = 31 | No sputum culture conversion N = 37 | Univariate model | Multivariate model | ||
|---|---|---|---|---|---|---|
OR (95%CI) | P value | OR (95%CI) | P value | |||
Sex, female | 23 (74.2%) | 23 (62.2%) | 1.75 (0.62–4.97) | 0.293 |  |  |
Age (years), median (IQR) | 58 (50–67) | 61 (44–47.5) | 1.00 (0.97–1.03) | 0.953 |  |  |
Species/complex | ||||||
 MAC | 17 (54.8%) | 20 (54.1%) | 1.02 (0.38–2.73) | 0.969 |  |  |
 M. abscessus | 3 (9.7%) | 10 (27%) | 0.28 (0.76–22.23) | 0.073 | 0.87 (0.18–4.28) | 0.868 |
 M. xenopi | 6 (19.4%) | 2 (5.4%) | 4.12 (0.76–22.23) | 0.099 | 9.50 (0.68–131.82) | 0.094 |
 MAC/M. xenopi | 1 (3.2%) | 2 (5.4%) |  |  |  |  |
 Macrolide resistant MAC | 2 (6.5%) | 3 (8.1%) | 0.76 (0.12–4.89) | 0.774 |  |  |
 M. simiae | 1 (3.2%) | 0 |  |  |  |  |
 M. fortuitum | 1 (3.2%) | 0 |  |  |  |  |
FC pattern | 13 (35.1%) | 13 (41.9%) | 1.33 (0.50–3.56) | 0.566 |  |  |
Cavity | 21 (67.7%) | 23 (62.2%) | 1.28 (0.47–3.49) | 0.632 |  |  |
AFB positive ever | 30 (96.8%) | 37 (100%) | 3.69 (0.15–93.81) | 0.791 |  |  |
Total dose AK per bodyweight (g/kg), median (IQR)b | 0.79 (0.55–2.29) | 1.20 (0.74–2.09) | 0.81 (0.55–1.18) | 0.268 | 0.54 (0.26–1.10) | 0.089 |
Weekly dose AK per bodyweight (mg/kg/week), median (IQR)a | 26.09 (23.61–33.87) | 27.03 (22.6–40.3) | 0.98 (0.94–1.03) | 0.438 |  |  |
Months on AK, median (IQR) | 8 (4–18) | 8 (6–15) | 0.98 (0.94–1.02) | 0.356 |  |  |
Total dose AK (g), Median (IQR)c | 46.8 (29.4–130.3) | 60.3 (37.8–118.0) | 1.00 (0.99–1.01) | 0.725 |  |  |
Surgery | 19 (61.3%) | 2 (5.4%) | 27.7 (5.61–136.9) | < 0.001 | 33.01 (4.79–227.27) | < 0.001 |