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Table 1 The length of time at which adverse effect significantly manifested on Balb c mice treated with test chemicals orally

From: Study of the principles in the first phase of experimental pharmacology: the basic step with assumption hypothesis

Test chemical Doses tested № of Mice Weight in gm Time at which test substance administered Time at which signs of adverse effect clearly manifested Duration
1.1.Dichlorvos 10 mg/kg 1 15.13 10:22 11:22 1 h
50 mg/kg 1 17.63 10:23 10:53 30 min
90 mg/kg 1 16.42 10:24 10:39 15 min
1.1.Chlorpyrifos 10 mg/kg 1 30.41 10:28 13:00 2:30 h
50 mg/kg 1 27.12 10:29 12:00 1:30 h
90 mg/kg 1 26.84 10:30 11:00 30 min
1.1.Cypermethrin 10 mg/kg 1 28.42 10:32 10:55 23 min
50 mg/kg 1 30.98 10:33 10:45 12 min
90 mg/kg 1 28.24 10:36 10:45 9 min
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