Dose in mg/kg | 10 | 50 | 90 |
Number of mice treated | 1 | 1 | 1 |
Adverse effects within 24 hrs | ❖ Hypo-activity ❖ Weak ❖ Slow respiration | ❖ Hypo-activity ❖ Weak ❖ Slow respiration | ❖ Hypo-activity ❖ Weak ❖ Slow respiration ❖ Died after 1:36 hours |
Adverse effects within 48 hrs | ❖ Increased activity | ❖ Slightly increased activity | |
Adverse effects within 72 hrs | ❖ Recovered | ❖ Slightly recovered | |
Adverse effects within 96 hrs | ❖ Completely recovered | ❖ Recovered | |
Adverse effects within 120 hrs | ❖ Weight loss | ❖ Weight loss |