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Table 8 The effect of different doses of Cypermethrin on Balb c mice which were administered orally using interagasteral tube

From: Study of the principles in the first phase of experimental pharmacology: the basic step with assumption hypothesis

Dose in mg/kg 10 50 90
Number of mice treated 1 1 1
Adverse effect within 24 hrs ❖ Distended stomach
❖ Bulging eyes
❖ Salivating
❖ Breathing difficulty
❖ Tremor
❖ Distended stomach
❖ Bulging eyes
❖ Salivating
❖ Breathing difficulty
❖ Tremor
❖ Distended stomach
❖ Bulging eyes
❖ Salivating
❖ Breathing difficulty
❖ Tremor & died after 11:36 hrs
Adverse effect within 48 hrs ❖ Slightly improved but with still breathing difficulty ❖ Died after 26:00 hrs  
Adverse effect within 72 hrs ❖ Breathing difficulty   
Adverse effect within 96 hrs ❖ Slightly recovered   
Adverse effect within 120 hrs ❖ Weight loss   
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