Table 1 Baseline characteristics
Characteristica | Enoxaparin 20 mg SC Daily (n = 16) | Enoxaparin 30 mg SC Daily (n = 11) | P-value |
|---|---|---|---|
Age (years) | 83.8 ± 6.9 | 82.1 ± 6.4 | 0.52 |
BMI (Kg/m2) | 24.1 ± 3.4 | 28.0 ± 6.3 | 0.16 |
Weight (Kg) | 63.1 ± 8.3 | 70.2 ± 12.3 | 0.11 |
Padua score | 3.5 ± 1.5 | 3.3 ± 2.1 | 0.74 |
Female Gender (%) | 68.8 (11/16) | 81.8 (9/11) | 0.66 |
Alcohol Use (%) | 18.8 (3/16) | 36.4 (4/11) | 0.39 |
ICU Admission (%) | 37.5 (6/16) | 18.2(2/11) | 0.41 |
Chronic Kidney disease (%) | 62.5 (10/16) | 54.5 (6/11) | 0.71 |
CrCl on day 1 (%) | |||
 < 20 | 56.3 (9/16) | 36.4 (4/11) | 0.54 |
 20–29 | 25.0 (4/16) | 27.3 (3/11) |  |
 30–35 | 18.8 (3/16) | 36.4 (4/11) |  |
 CAD (%) | 43.8 (7/16) | 45.5 (5/11) | 0.99 |
 Diabetes (%) | 43.8 (7/16) | 54.5 (6/11) | 0.70 |
 CHF (%) | 56.3 (9/16) | 9.1 (1/11) | 0.02 |
 Cancer (%) | 25.0 (4/16) | 36.4 (4/11) | 0.68 |
Antiplatelet use on admission | |||
 Aspirin (%) | 56.3 (9/16) | 54.5 (6/11) | 0.99 |
 Clopidogrel (%) | 12.5 (2/16) | 27.3 (1/11) | 0.99 |
Concomitant medications during hospitalization | |||
 ARBs (%) | 25.0 (4/16) | 9.1 (1/11) | 0.51 |
 Statin (%) | 37.5 (6/16) | 27.3 (3/11) | 0.69 |
 Aspirin 81 mg–100 mg (%) | 56.2 (9/16) | 63.6 (8/11) | 0.99 |
 Clopidogrel 75 mg (%) | 18.7 (3/16) | 9.1 (1/11) | 0.62 |
 Loop diuretics PO (%) | 12.5 (2/16) | 27.3 (3/11) | 0.37 |
 Loop diuretics IV (%) | 50.0 (8/16) | 36.4 (4/11) | 0.70 |
 Aldosterone antagonists (%) | 6.2 (1/16) | 9.1 (1/11) | 0.99 |
Laboratory trends | |||
 Lab day 1 potassium (mEq/L) | 4.52 ± 0.93 | 4.60 ± 0.86 | 0.83 |
 Lab day 3 potassium (mEq/L) | 4.33 ± 0.77 | 3.95 ± 0.66 | 0.22 |
 Lab day 1 hemoglobin (g/dL) | 10.33 ± 2.08 | 11.29 ± 1.66 | 0.29 |
 Lab day 3 hemoglobin (g/dL) | 9.58 ± 1.51 | 10.48 ± 1.50 | 0.22 |
 Lab day 1 Platelets, (per microliter) | 270,692 ± 148,970 | 302,250 ± 133,511 | 0.63 |
 Lab day 3 Platelets (per microliter) | 206,333 ± 63,532 | 263,428 ± 86,061 | 0.12 |
 Lab day 1 SCr (mg/dL) | 2.62 ± 1.25 | 2.15 ± 1.13 | 0.34 |
 Lab day 3 SCr (mg/dL) | 2.82 ± 1.22 | 2.31 ± 1.76 | 0.37 |
 Mean SCr (mg/dL) | 2.72 ± 1.15 | 2.28 ± 1.46 | 0.39 |
 Lab day 1 CrCl (mg/dL) | 19.71 ± 8.76 | 24.57 ± 8.13 | 0.15 |
 Lab Day 3 CrCl (mL/min) | 17.52 ± 6.75 | 28.22 ± 14.52 | 0.02 |
 Mean CrCl (mg/dL) | 18.55 ± 7.33 | 25.97 ± 10.49 | 0.04 |