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Table 1 Patients’ demographic characteristics

From: Acute versus chronic methotrexate poisoning; a cross-sectional study

No. Age range (year) Sex Diagnosis of the basal illness Dose of MTX Period of MTX usage before the event Type of event Other drugs
1a 60–69 Male RA Undetermined Undetermined LOC, skin and mucosal lesions
2 2–9 Male Accidental Undetermined 1 day Nausea and vomiting
3 2–9 Female Accidental Undetermined 1 day  
4 60–69 Female RA 15 mg More than 6 months Mucosal lesions, nausea, vomiting, diarrhea, abdominal pain Folic acid and hydroxychlorocin daily regularly
5 60–69 Female RA 70 mg/week instead of 10 mg/week More than 6 months Mucosal lesions
6 40–49 Male Suicidal 50 mg 1 day
7 20–29 Female Suicidal 2.5× undetermined number 1 day Nausea and vomiting
8 30–39 Female Psoriasis Suicidal (MDT) 5 mg Undetermined Nausea and vomiting, drowsiness Multi drug toxicity (MTX + Respiridone)
9 50–59 Female RA 2.5× undetermined number 10 days Mucosal lesion, diarrhea, GI bleeding
10 10–19 Female Suicidal 2.5× undetermined number 1 day Nausea and vomiting
11 10–19 Female Suicidal 87.5 mg 1 day Nausea and vomiting
12 40–49 Female Suicidal 125 mg 1 day
13 50–59 Female RA Suicidal 150 mg Undetermined
14 10–19 Male Suicidal 75 mg 1 day Nausea and vomiting
15 70–79 Female RA 70 mg/week instead of 10 mg/week 11 days Mucosal lesions
16 50–59 Female Suicidal (MDT) 50 mg 1 day MTX+ diazepam+ acetaminophen
17 2–9 Male Accidental 20 mg 1 day  
18 10–19 Female Suicidal 12.5 mg 1 day MTX+ Prednisolone+ Azathioprine
19 40–49 Female SLE 50 mg/week instead of 15 mg/week Undetermined Mucosal lesions
20 70–79 Female RA 50 mg/week instead of 15 mg/week More than 2 months Mucosal lesions
21 30–39 Female Psoriasis, SLE 10 mg weekly More than 1 year Skin and mucosal lesions, GIB Azathioprine
22 30–39 Female SLE 7.5 mg weekly More than 6 months Skin and mucosal lesions Did not take the prescribed Folic acid
23 50–59 Female RA 7.5 mg/day instead to 7.5 mg/week Undetermined Mucosal lesions, nausea, vomiting, diarrhea Did not take the prescribed Folic Acid
24 50–59 Female RA 50 mg weekly instead of 25 mg weekly 1.5 month Skin and mucosal lesions, abdominal pain, GIB
25 40–49 Female RA Amp 1000 mg instead of 50 mg weekly 3 weeks Skin and mucosal lesions, nausea and vomiting, abdominal pain
26 70–79 Female RA 17.5 mg instead of 2.5 mg weakly More than 6 months Mucosal lesions, nausea, vomiting, diarrhea, abdominal pain
27 50–59 Female RA 30 mg/week instead of 15 mg/week More than 4 months Skin and mucosal lesions Cyclosporine
  1. aThe only case of mortality