Table 2 Comparison of the lab test results between patients with acute and chronic poisonings
From: Acute versus chronic methotrexate poisoning; a cross-sectional study
Acute (n = 13) | Chronic (n = 14) | P | Total (n = 27) | |
|---|---|---|---|---|
Median [IQR] Creatinine (mg/dL) | 0.8 [0.7, 1.1] | 1.0 [0.9, 1.4] | 0.048 | 1.0 [0.8, 1.1] |
(min, max) | (0.6, 1.2) | (0.7, 2.1) | (0.6, 2.1) | |
Median [IQR] BUN (mg/dL) | 11 [10, 12] | 21 [16, 35.7] | < 0.001 | 15 [11, 22] |
(min, max) | [8, 15] | (13, 80) | [8, 80] | |
Mean Total bilirubin (SD) (mg/L) | 0.9 ± 0.4 | 1.2 ± 0.7 | 0.304 | 1.04 ± 0.62 |
(min, max) | (0.5, 1.7) | (0.3, 2.9) | (0.3, 2.9) | |
Median [IQR] Direct bilirubin (mg/L) | 0.20 [0.12, 0.20] | 0.20 [0.12, 0.55] | 0.238 | 0.20 [0.20, 0.4] |
(min, max) | (0.1, 0.6) | (0.1, 0.6) | (0.1, 2.0) | |
Median [IQR] INR (IU) | 1.0 [1.0, 1.1] | 1.0 [0.9, 1.1] | 0.272 | 1.0 [0.9, 1.1] |
(min, max) | (0.9, 1.2) | (0.9, 2.0) | (0.9, 2.0) | |
Mean (SD) WBC (/mm3) | 8313 ± 3761 | 2050 ± 1251 | < 0.001 | 5066 ± 4181 |
(min, max) | (1480, 15200) | (400, 4400) | (400, 15,200) | |
Mean Hgb (SD) (mg/dL) | 12.7 ± 2.1 | 9.1 ± 1.3 | < 0.001 | 10.8 ± 2.5 |
(min, max) | (9.0, 16.7) | (6.5, 11.3) | (6.5, 16.7) | |
Mean Platelet (SD) (/mm3) | 253846 ± 56388 | 78500 ± 39868 | < 0.001 | 162925± 101161 |
(min, max) | (134000, 326000) | (35000, 147000) | (40000, 326000) | |
Mean PCo2 (SD) (mmHg) | 39.6 ± 5.07 | 34.3 ± 8.56 | 0.093 | 37.1 ± 7.3 |
(min, max) | (28.0, 46.7) | (20.7, 45.0) | (20.7, 46.7) | |
Mean HCo3 (SD) (mEq/L) | 24.8 ± 4.3 | 23.8 ± 5.0 | 0.627 | 24.4 ± 4.5 |
(min, max) | (19.3, 34.8) | (16.0, 30.7) | (16, 34) | |
Mean PTT (SD) (seconds) | 31 ± 4 | 31 ± 6 | 0.077 | 30 ± 4.7 |
(min, max) | (25, 38) | (24, 40) | (24, 39) | |
Mean Urine (SD) pH* | 6.4 ± 1.2 | 6.2 ± 1.0 | 0.714 | 6.3 ± 1.0 |
(min, max) | (5, 7.5) | (5, 7.5) | (5, 7.5) |