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Table 1 Comparison of Patients Characteristics According to Mortality due to ADRs events

From: Development of a mortality score to assess risk of adverse drug reactions among hospitalized patients with moderate to severe chronic kidney disease

 

No. (%) of participants

 

Characteristics

Survived (n = 132)

Died (n = 28)

p value

Demographics

 Age

  

0.888

   ≤ 49 years

34 (21.3)

7 (4.4)

 

  50–59 years

32 (20.0)

8 (5.0)

 

   ≥ 60 years

66 (41.3)

13 (8.1)

 

 Gender

  

0.643

  Male

77 (48.1)

15 (9.4)

 

  Female

55 (34.4)

13 (8.1)

 

 Ethnicity

  Malay

44 (27.5)

8 (5.0)

0.626

  Chinese

57 (35.6)

11 (6.9)

 

  Indian

27 (18.1)

9 (5.6)

 

  Currently or previously smoking

34 (21.3)

7 (4.4)

0.934

  Currently or previously consumed alcohol

19 (11.9)

4 (2.5)

0.988

 Renal Replacement Therapy

  

0.750

  Haemodialysis

52 (32.5)

9 (5.6)

 

  Peritoneal dialysis

10 (6.3)

2 (1.3)

 

  Conservative management

70 (43.8)

17 (10.6)

 

 Renal Function

  

0.041

  30–59 mL/min/1.73m2

46 (28.7)

3 (1.9)

 

  15–29 mL/min/1.73m2

22 (13.8)

7 (4.4)

 

   < 15 mL/min/1.73m2

64 (40.0)

18 (11.3)

 

 Physical examinations

  Systolic, mean (SD), mm Hg

132 (100)

28 (100)

0.486

  Diastolic, median (IQR), mm Hg

132 (100)

28 (100)

0.159

 Comorbid conditions

  Diabetes

89 (67.4)

17 (60.7)

0.495

  Dyslipidaemia

65 (40.6)

7 (4.4)

0.019

  Hypertension

6 (3.8)

22 (13.8)

0.547

  UTI

3 (1.9)

4 (2.5)

0.005

 Laboratory data

  Serum Albumin, mean (SD), g/L

132 (100)

28 (100)

< 0.001

  Serum Alkaline Phosphatase, median (IQR), U/L

131 (99)

28 (100)

0.009

  Serum Aspartate Aminotransferase, median (IQR), U/L

94 (71)

22 (79)

0.009

  Serum CO2, mean (SD), mmol/L

116 (88)

26 (93)

0.020

  Serum C-Reactive Protein, median (IQR), mg/L

62 (47)

23 (82)

< 0.001

  Serum Lactate Dehydrogenase, median (IQR), U/L

94 (71)

23 (82)

< 0.001

  Serum Low Density Lipoprotein (LDL), mean (SD), mmol/L

62 (50)

6 (21)

< 0.001

  VMedications use

  Total medication, median (IQR)

132 (100)

28 (100)

< 0.001