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Table 1 The results of biochemical evaluations of serum samples among groups

From: The effects of thiamine pyrophosphate on ethanol induced optic nerve damage

 

HC (n:6)

EtOH (n:6)

TEt-20 (n:6)

TPG (n:6)

p

sIL-1β

3.60 ± 0.35b,c

8.15 ± 0.35a,c,d

4.23 ± 0.48a,b,d

3.83 ± 0.36b,c

0.001

sTNF-α

2.85 ± .018b,c

6.53 ± 0.41a,c,d

3.51 ± 0.31a,b,d

3.08 ± 0.194b,c

0.001

sMDA

1.75 ± 0.18b,c

4.78 ± 0.19a,c,d

2.21 ± 0.27a,b,d

1.58 ± 0.24b,c

0.001

sGSH

5.91 ± 0.26b,c

1.61 ± 0.33a,c,d

5.16 ± 0.16a,b,d

6.31 ± 0.33b,c

0.001

  1. HC Healthy controls, EtOH ethanol group, TEt-20 ethanol + thiamine pyrophosphate group, TPG thiamine pyrophosphate group. MDA Malondialdehyde, GSH total glutathione, IL-1β interleukin 1 beta, TNF-α tumor necrosis factor alpha, s serum. a: statistically significantly different compared with HC; b: statistically significantly different compared with EtOH; c: statistically significantly different compared with TEt-20; d: statistically significantly different compared with TPG. (Statistical significance was set at p < 0.05)