
HC (n:6)

EtOH (n:6)

TEt20 (n:6)

TPG (n:6)

p


tIL1β

2.18 ± 0.19^{b,c}

4.98 ± 0.37^{a,c,d}

2.71 ± 0.19^{a,b,d}

2.51 ± 0.21^{b,c}

0.001

tTNFα

1.10 ± 0.12^{b,c}

3.21 ± 0.23^{a,c,d}

1.70 ± 0.14^{a,b,d}

1.38 ± 0.13^{b,c}

0.001

tMDA

0.95 ± 0.03^{b,c}

3.31 ± 0.27^{a,c,d}

1.35 ± 0.18^{a,b,d}

0.92 ± 0.03^{b,c}

0.001

tGSH

4.91 ± 0.24^{b,c}

1.41 ± 0.36^{a,c,d}

4.10 ± 0.31^{a,b,d}

5.30 ± 0.34^{b,c}

0.001

 HC Healthy controls, EtOH ethanol group, TEt20 ethanol + thiamine pyrophosphate group, TPG thiamine pyrophosphate group. MDA Malondialdehyde, GSH total glutathione, IL1β interleukin 1 beta, TNFα tumor necrosis factor alpha, t tissue. HC Healthy controls, EtOH ethanol group, TEt20 ethanol + thiamine pyrophosphate group, TPG thiamine pyrophosphate group. MDA Malondialdehyde, GSH total glutathione, IL1β interleukin 1 beta, TNFα tumor necrosis factor alpha, s serum. ^{a}: statistically significantly different compared with HC; ^{b}: statistically significantly different compared with EtOH; ^{c}: statistically significantly different compared with TEt20; ^{d}: statistically significantly different compared with TPG. (Statistical significance was set at p < 0.05)