| |
HC (n:6)
|
EtOH (n:6)
|
TEt-20 (n:6)
|
TPG (n:6)
|
p
|
|---|
|
tIL-1β
|
2.18 ± 0.19b,c
|
4.98 ± 0.37a,c,d
|
2.71 ± 0.19a,b,d
|
2.51 ± 0.21b,c
|
0.001
|
|
tTNF-α
|
1.10 ± 0.12b,c
|
3.21 ± 0.23a,c,d
|
1.70 ± 0.14a,b,d
|
1.38 ± 0.13b,c
|
0.001
|
|
tMDA
|
0.95 ± 0.03b,c
|
3.31 ± 0.27a,c,d
|
1.35 ± 0.18a,b,d
|
0.92 ± 0.03b,c
|
0.001
|
|
tGSH
|
4.91 ± 0.24b,c
|
1.41 ± 0.36a,c,d
|
4.10 ± 0.31a,b,d
|
5.30 ± 0.34b,c
|
0.001
|
- HC Healthy controls, EtOH ethanol group, TEt-20 ethanol + thiamine pyrophosphate group, TPG thiamine pyrophosphate group. MDA Malondialdehyde, GSH total glutathione, IL-1β interleukin 1 beta, TNF-α tumor necrosis factor alpha, t tissue. HC Healthy controls, EtOH ethanol group, TEt-20 ethanol + thiamine pyrophosphate group, TPG thiamine pyrophosphate group. MDA Malondialdehyde, GSH total glutathione, IL-1β interleukin 1 beta, TNF-α tumor necrosis factor alpha, s serum. a: statistically significantly different compared with HC; b: statistically significantly different compared with EtOH; c: statistically significantly different compared with TEt-20; d: statistically significantly different compared with TPG. (Statistical significance was set at p < 0.05)