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Table 2 The results of biochemical evaluations of tissue samples among groups

From: The effects of thiamine pyrophosphate on ethanol induced optic nerve damage

  HC (n:6) EtOH (n:6) TEt-20 (n:6) TPG (n:6) p
tIL-1β 2.18 ± 0.19b,c 4.98 ± 0.37a,c,d 2.71 ± 0.19a,b,d 2.51 ± 0.21b,c 0.001
tTNF-α 1.10 ± 0.12b,c 3.21 ± 0.23a,c,d 1.70 ± 0.14a,b,d 1.38 ± 0.13b,c 0.001
tMDA 0.95 ± 0.03b,c 3.31 ± 0.27a,c,d 1.35 ± 0.18a,b,d 0.92 ± 0.03b,c 0.001
tGSH 4.91 ± 0.24b,c 1.41 ± 0.36a,c,d 4.10 ± 0.31a,b,d 5.30 ± 0.34b,c 0.001
  1. HC Healthy controls, EtOH ethanol group, TEt-20 ethanol + thiamine pyrophosphate group, TPG thiamine pyrophosphate group. MDA Malondialdehyde, GSH total glutathione, IL-1β interleukin 1 beta, TNF-α tumor necrosis factor alpha, t tissue. HC Healthy controls, EtOH ethanol group, TEt-20 ethanol + thiamine pyrophosphate group, TPG thiamine pyrophosphate group. MDA Malondialdehyde, GSH total glutathione, IL-1β interleukin 1 beta, TNF-α tumor necrosis factor alpha, s serum. a: statistically significantly different compared with HC; b: statistically significantly different compared with EtOH; c: statistically significantly different compared with TEt-20; d: statistically significantly different compared with TPG. (Statistical significance was set at p < 0.05)