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Table 3 Prognostic effects of drugs in CAD patients with and without low GFR

From: Relationship between drug application and mortality rate in Chinese older coronary artery disease/chronic heart failure patients with and without low glomerular filtration rate

DrugsWithout low GFRWith low GFR
Survival time (days)P value*P value**Survival time (days)P value*P value**
No useUseNo useUse
Aspirin883 (828–937)1086 (1019–1152)0.0230.173900 (785–1015)813 (718–908)0.3490.445
Clopidogrel946 (877–1015)1088 (1024–1153)0.0080.028942 (835–1050)739 (646–832)0.7180.871
Beta-blockers964 (915–1014)1024 (961–1088)0.1550.4361118 (1017–1220)724 (635–813)0.0130.388
CCBs899 (840–958)1062 (996–1129)0.2090.499711 (602–821)910 (808–1013)0.4320.223
Nitrates903 (841–965)1038 (981–1095)0.2460.692908 (760–1056)867 (769–966)0.2250.460
ACEI/ARBs1026 (947–1105)1077 (1007–1148)0.0330.426816 (698–934)835 (745–926)0.0460.671
Statins903 (821–986)1136 (1077–1194)< 0.001< 0.001796 (656–937)811 (729–892)0.0020.225
  1. *Relationship of drugs with survival time was bivariately evaluated with Kaplan-Meier analysis; **relationship of drugs with mortality rate was multivariately adjusted by age, gender, body mass index, CAD, CHF, atrial fibrillation, hypertension, heart rate, systolic blood pressure, diastolic blood pressure, hemoglobin, albumin, glomerular filtration rate, fasting plasma glucose, triglyceride, low density lipoprotein cholesterol and high density lipoprotein cholesterol using Cox Regression
  2. Abbreviations: ACEI/ARBs Renin-angiotensin-aldosterone system inhibitors/angiotensin receptor blockers, CAD Coronary artery disease, CHF Chronic heart failure, CCBs Calcium channel blockers, GFR Glomerular filtration rate