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Fig. 2 | BMC Pharmacology and Toxicology

Fig. 2

From: Influence of N-acetyl-L-cysteine against bisphenol a on the maturation of mouse oocytes and embryo development: in vitro study

Fig. 2

Effect of 100 μM NAC on the inhibition of poly body emission by 50 μg/mL BPA. C, control; NAC, 100 μM N-acetyl-L-cysteine; BPA, 50 μg/mL bisphenol A; NAC + BPA, combined treatment with NAC (100 μM) and BPA (50 μg/mL). The rates of polar body emission (%) in the control, NAC, BPA and NAC + BPA groups were 95.3 ± 1.5, 94.7 ± 1.4, 72.3 ± 3.3 and 90.8 ± 1.9, respectively. After maturation in the presence of 100 μM NAC and,50 μg/mL BPA, the rate of polar body emission in the NAC + BPA co-treated group was somewhat normalized. Each treatment was repeated 3 times, with each replicate containing 30–40 oocytes. a-cValues with different superscripted letters above the bars differ significantly (P < 0.05)

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