|
Bisphenol A Concentration(μg/mL)
|
Time (h)
|
Oocytes (n)
|
Oocytes with polar body extrusion (n)
|
Polar body extrusion rate (% ± SEM)
|
|---|
|
(Control)0
|
14
|
102
|
96
|
94.1 ± 1.6a
|
|
20
|
14
|
101
|
94
|
93.0 ± 1.1a
|
|
50
|
14
|
103
|
78
|
75.7 ± 2.0b
|
|
100
|
14
|
104
|
41
|
38.6 ± 3.2c
|
- Mouse oocytes were cultured in maturation medium with 0, 20, 50, or 100 μg/mL BPA for 14 h, Then, the number of oocytes with polar body emission was recorded. Each treatment was repeated 3 times, and each replicate contained 30–40 oocytes. The data were analysed with one-way ANOVA and Dunnett’s post- hoc test. a-cValues with different superscripts in the same column are significantly different (P < 0.05)
