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Table 1 Effects of BPA on the frequency of first polar body extrusion

From: Influence of N-acetyl-L-cysteine against bisphenol a on the maturation of mouse oocytes and embryo development: in vitro study

Bisphenol A Concentration(μg/mL) Time (h) Oocytes (n) Oocytes with polar body extrusion (n) Polar body extrusion rate (% ± SEM)
(Control)0 14 102 96 94.1 ± 1.6a
20 14 101 94 93.0 ± 1.1a
50 14 103 78 75.7 ± 2.0b
100 14 104 41 38.6 ± 3.2c
  1. Mouse oocytes were cultured in maturation medium with 0, 20, 50, or 100 μg/mL BPA for 14 h, Then, the number of oocytes with polar body emission was recorded. Each treatment was repeated 3 times, and each replicate contained 30–40 oocytes. The data were analysed with one-way ANOVA and Dunnett’s post- hoc test. a-cValues with different superscripts in the same column are significantly different (P < 0.05)