Table 6 Prescribed drugs’ doses of the top-10 interactions
From: Potential drug-drug interactions among pneumonia patients: do these matter in clinical perspectives?
Interacting pair | Dose categoriesa | Prescribed dose regimen | Number of patients |
|---|---|---|---|
Aspirin + Furosemide | Low + Low | 75 mg OD + 40 mg OD | 17 |
Low + High | 75 mg OD + 60 mg OD | 10 | |
Low + Low | 75 mg OD + 20 mg OD | 5 | |
Low + High | 75 mg OD + 100 mg OD | 3 | |
Low + High | 75 mg OD + 40 mg BD | 2 | |
Low + High | 75 mg OD + 60 mg BD | 2 | |
Low + High | 75 mg OD + 80 mg OD | 1 | |
Furosemide + Hydrocortisone | Low + High | 40 mg OD + 100 mg QID | 5 |
High + High | 80 mg OD + 100 mg QID | 4 | |
Low + Low | 40 mg OD + 250 mg OD | 3 | |
High + Low | 60 mg OD + 50 mg QID | 3 | |
High + High | 60 mg OD + 100 mg QID | 3 | |
Low + High | 20 mg OD + 100 mg QID | 3 | |
Low + High | 20 mg OD + 500 mg OD | 2 | |
Low + Low | 40 mg OD + 50 mg QID | 2 | |
High + Low | 60 mg OD + 250 mg OD | 2 | |
High + Low | 40 mg BD + 50 mg BD | 1 | |
Low + High | 40 mg OD + 250 mg TDS | 1 | |
High + High | 60 mg OD + 500 mg TDS | 1 | |
High + Low | 60 mg BD + 100 mg TDS | 1 | |
Low + Low | 40 mg OD + 100 mg BD | 1 | |
High + Low | 60 mg OD + 100 mg BD | 1 | |
High + High | 80 mg BD + 100 mg QID | 1 | |
High + Low | 60 mg BD + 250 mg OD | 1 | |
High + Low | 80 mg OD + 250 mg OD | 1 | |
High + High | 100 mg OD + 100 mg QID | 1 | |
High + High | 80 mg OD + 500 mg QID | 1 | |
High + Low | 60 mg BD + 50 mg TDS | 1 | |
Aspirin + Clopidogrel | Low + Low | 75 mg OD + 75 mg OD | 35 |
High + Low | 150 mg OD + 75 mg OD | 1 | |
High + Low | 300 mg OD + 75 mg OD | 1 | |
Aspirin + Insulin | Low + High | 75 mg OD + 20–40 units/day | 21 |
Low + High | 75 mg OD + > 40 units/day | 6 | |
Low + Low | 75 mg OD + < 20 units/day | 5 | |
High + Low | 150 mg OD + 20 units/day | 1 | |
Isoniazid + Rifampin | Low + Low | 75 mg OD + 150 mg OD | 27 |
High + High | 150 mg OD + 300 mg OD | 6 | |
Calcium containing products + Ceftriaxone | Low + Low | 200 mg/L OD + 2 g OD ATD | 7 |
Low + High | 200 mg/L BD + 2 g BD ATD | 5 | |
Low + Low | 200 mg/L BD + 2 g OD ATD | 4 | |
High + Low | 1 g OD + 2 g OD ATD | 4 | |
Low + Low | 200 mg/L OD + 1 g BD ATD | 3 | |
Low + Low | 200 mg/L TDS + 2 g OD ATD | 2 | |
High + High | 1 g OD + 2 g BD ATD | 1 | |
Low + Low | 200 mg/L BD + 1 g BD ATD | 1 | |
Low + Low | 200 mg/L OD + 1 g OD ATD | 1 | |
Low + Low | 200 mg/L BD + 1 g OD ATD | 1 | |
Low + High | 200 mg/L BD + 3 g BD ATD | 1 | |
Low + High | 200 mg/L OD + 4 g OD ATD | 1 | |
High + High | 1250 mg BD + 2 g BD ATD | 1 | |
High + Low | 1250 mg OD + 2 g OD ATD | 1 | |
Pyrazinamide + Rifampin | Low + Low | 400 mg OD + 150 mg OD | 28 |
High + High | 500 mg OD + 300 mg OD | 4 | |
Aspirin + Ramipril | Low + Low | 75 mg OD + 2.5 mg OD | 20 |
Low + High | 75 mg OD + 5 mg OD | 4 | |
Low + High | 75 mg OD + 10 mg OD | 3 | |
Low + Low | 75 mg OD + 1.25 mg OD | 1 | |
Albuterol + Furosemide | High + Low | 5 mg/ml TDS + 40 mg OD | 13 |
High + High | 5 mg/ml TDS + 60 mg OD | 8 | |
High + Low | 5 mg/ml TDS + 20 mg OD | 4 | |
High + High | 5 mg/ml TDS + 40 mg BD | 1 | |
Low + Low | 50mcg/actuation TDS + 40 mg OD | 1 | |
Low + High | 2 mg OD + 80 mg BD | 1 | |
Aspirin + Bisoprolol | Low + Low | 75 mg OD + 2.5 mg OD | 14 |
Low + High | 75 mg OD + 5 mg OD | 7 | |
High + High | 300 mg OD + 5 mg OD | 1 | |
High + Low | 150 mg OD + 2.5 mg OD | 1 |