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Table 4 Factors associated with the occurrence of neurological severe adverse effects following ivermectin treatment in DRC between 2003 and 2017 – multivariate analysis

From: Analysis of severe adverse effects following community-based ivermectin treatment in the Democratic Republic of Congo

Parameter category Adjusted OR (95% CI) P-value
Sex
 Male 1.9 (1.4–2.7)  
 Female 1 < 0.001
Age (years)
  ≤ 18 1  
 19–35 15.0 (7.7–29.1) < 0.001
  ≥ 36 8.1 (4.2–15.4) < 0.001
Alcohol consumption 24 h before ivermectin treatment
 Yes 2.8 (2.1–3.8) < 0.001
 No 1  
Hemp consumption 24 h before ivermectin treatment
 Yes 2.3 (1.4–3.9) < 0.001
 No 1  
Associated diseases
 Loiasis   
 Yes 3.4 (2.1–5.5) < 0.001
 No 1  
  1. OR = Odds ratio, CI = confidence interval