Table 4 Factors associated with the occurrence of neurological severe adverse effects following ivermectin treatment in DRC between 2003 and 2017 – multivariate analysis
Parameter category | Adjusted OR (95% CI) | P-value |
|---|---|---|
Sex | ||
Male | 1.9 (1.4–2.7) | |
Female | 1 | < 0.001 |
Age (years) | ||
≤ 18 | 1 | |
19–35 | 15.0 (7.7–29.1) | < 0.001 |
≥ 36 | 8.1 (4.2–15.4) | < 0.001 |
Alcohol consumption 24 h before ivermectin treatment | ||
Yes | 2.8 (2.1–3.8) | < 0.001 |
No | 1 | |
Hemp consumption 24 h before ivermectin treatment | ||
Yes | 2.3 (1.4–3.9) | < 0.001 |
No | 1 | |
Associated diseases | ||
Loiasis | ||
Yes | 3.4 (2.1–5.5) | < 0.001 |
No | 1 | |