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Fig. 4 | BMC Pharmacology and Toxicology

Fig. 4

From: Efficacy of a topical gabapentin gel in a cisplatin paradigm of chemotherapy-induced peripheral neuropathy

Fig. 4

Effect of topical gabapentin 10% gel (GBP-10%), topical control gel (CG) and systemic gabapentin at 75 mg/kg (GBP-75, i.p.) on footprint pattern analysis after weekly i.p. injection of cisplatin (Cis) at 3.0 mg/kg (Cis-3) for four consecutive weeks in rats. The measured parameter was expressed as the overlap distance between the forepaw and hind paw placements, 1 h post treatment. Each symbol represents the mean paw overlap in cm ± SEM. ***P < 0.001 as compared to the saline (Sal) treated control group, two-way repeated measures ANOVA followed by post hoc Bonferroni’s analysis; n = 6 rats per group

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